{"_buckets": {"deposit": "e27112da-088e-410a-9698-a2431772f0fb"}, "_deposit": {"created_by": 1, "id": "79586", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "79586"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00079586", "sets": ["29"]}, "author_link": ["857926", "857921", "857932", "857927", "857925", "857933", "857931", "857920", "857929", "857930", "857922", "857928", "857923", "857924"], "item_10005_date_7": {"attribute_name": "発表年月日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2020-02-03", "subitem_date_issued_type": "Issued"}]}, "item_10005_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "[64Cu]Cu-ATSMは脳腫瘍への治療効果が期待される放射性薬剤である。我々は無菌アイソレーターを用いて臨床用[64Cu]Cu-ATSM注射液を製造したので報告する。【方法】無菌アイソレーター内で過酸化水素ガス滅菌を行い、グレードA環境下でライン組み付けとリークチェックを行った。次に、原料のATSM/DMSO溶液を導入し、製造した64Cuグリシン溶液と混合し、さらにアスコルビン酸水溶液を加えてよく撹拌し[64Cu]Cu-ATSM注射液を合成した。【結果】[64Cu]Cu-ATSM注射液は3.0～3.7GBqの収量であり、64Cu製造後17～25分で合成し、回収率は約85％であった。作業者の被ばく量は30μSv程度であった。【結論】治験薬GMPに準拠した高品位の[64Cu]Cu-ATSM注射液を安定的に製造し、週1回4週連続の臨床提供を可能にした。", "subitem_description_type": "Abstract"}]}, "item_10005_description_6": {"attribute_name": "会議概要（会議名, 開催地, 会期, 主催者等）", "attribute_value_mlt": [{"subitem_description": "第１回千葉地区 技術と支援の活動報告会", "subitem_description_type": "Other"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "武井, 誠"}], "nameIdentifiers": [{"nameIdentifier": "857920", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "鈴木, 寿"}], "nameIdentifiers": [{"nameIdentifier": "857921", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "深田, 正美"}], "nameIdentifiers": [{"nameIdentifier": "857922", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "大矢, 智幸"}], "nameIdentifiers": [{"nameIdentifier": "857923", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "橋本, 裕輝"}], "nameIdentifiers": [{"nameIdentifier": "857924", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "河村, 和紀"}], "nameIdentifiers": [{"nameIdentifier": "857925", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "張, 明栄"}], "nameIdentifiers": [{"nameIdentifier": "857926", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takei, Makoto", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857927", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Hisashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857928", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fukada, Masami", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857929", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohya, Tomoyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857930", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hashimoto, Hiroki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857931", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawamura, Kazunori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857932", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ming-Rong, Zhang", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "857933", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "conference object", "resourceuri": "http://purl.org/coar/resource_type/c_c94f"}]}, "item_title": "無菌アイソレーターを用いた治験薬GMP準拠がん治療薬[64Cu]Cu-ATSM注射液製造", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "無菌アイソレーターを用いた治験薬GMP準拠がん治療薬[64Cu]Cu-ATSM注射液製造"}]}, "item_type_id": "10005", "owner": "1", "path": ["29"], "permalink_uri": "https://repo.qst.go.jp/records/79586", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-03-19"}, "publish_date": "2020-03-19", "publish_status": "0", "recid": "79586", "relation": {}, "relation_version_is_last": true, "title": ["無菌アイソレーターを用いた治験薬GMP準拠がん治療薬[64Cu]Cu-ATSM注射液製造"], "weko_shared_id": -1}