WEKO3
アイテム
Targeting cancer stem cells with miRNA-based strategies and particle radiation therapy
https://repo.qst.go.jp/records/72292
https://repo.qst.go.jp/records/72292a37a70f5-fbd4-4365-99e8-f7e2d1d91029
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-04-21 | |||||
| タイトル | ||||||
| タイトル | Targeting cancer stem cells with miRNA-based strategies and particle radiation therapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Vares, G.
× Vares, G.× Saintigny, Y.× Chevalier, F.× C.Lepleux× Hoh, H.× Jalleta, V.× Sai, Sei× Sugawara, H.× Nakajima, Tetsuo× 崔 星× 中島 徹夫 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Treatment resistance and relapse in challenging cancer models might be related to the presence of a small population of radio-resistant cancer stem cells. We have tested in vitro an approach combining high-LET carbon-ion therapy and CSC-targeted therapy, based on the modulation of micro-RNA expression by specific oligonucleotides (mimics and antagomirs), in three experimental models (pancreatic cancer, chondrosarcoma and triple-negative breast cancer). We identified several micro-RNA mimic treatments capable of improving carbon-ion therapy efficiency by targeting radioresistant CSCs in those models. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | H28年度HIMAC共同利用研究成果発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2017-04-17 | |||||
| 日付タイプ | Issued | |||||
