{"created":"2023-05-15T14:52:58.266336+00:00","id":72292,"links":{},"metadata":{"_buckets":{"deposit":"5bd57e9b-92d0-4722-9b19-61b89bf58a5d"},"_deposit":{"created_by":1,"id":"72292","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"72292"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00072292","sets":["10:28"]},"author_link":["712034","712032","712038","712029","712037","712036","712033","712031","712030","712039","712035"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-04-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Treatment resistance and relapse in challenging cancer models might be related to the presence of a small population of radio-resistant cancer stem cells. We have tested in vitro an approach combining high-LET carbon-ion therapy and CSC-targeted therapy, based on the modulation of micro-RNA expression by specific oligonucleotides (mimics and antagomirs), in three experimental models (pancreatic cancer, chondrosarcoma and triple-negative breast cancer). We identified several micro-RNA mimic treatments capable of improving carbon-ion therapy efficiency by targeting radioresistant CSCs in those models.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"H28年度HIMAC共同利用研究成果発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Vares, G."}],"nameIdentifiers":[{"nameIdentifier":"712029","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saintigny, Y."}],"nameIdentifiers":[{"nameIdentifier":"712030","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Chevalier, F."}],"nameIdentifiers":[{"nameIdentifier":"712031","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"C.Lepleux"}],"nameIdentifiers":[{"nameIdentifier":"712032","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hoh, H."}],"nameIdentifiers":[{"nameIdentifier":"712033","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jalleta, V."}],"nameIdentifiers":[{"nameIdentifier":"712034","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sai, Sei"}],"nameIdentifiers":[{"nameIdentifier":"712035","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugawara, H."}],"nameIdentifiers":[{"nameIdentifier":"712036","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakajima, Tetsuo"}],"nameIdentifiers":[{"nameIdentifier":"712037","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"崔 星","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"712038","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島 徹夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"712039","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Targeting cancer stem cells with miRNA-based strategies and particle radiation therapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Targeting cancer stem cells with miRNA-based strategies and particle radiation therapy"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-04-21"},"publish_date":"2017-04-21","publish_status":"0","recid":"72292","relation_version_is_last":true,"title":["Targeting cancer stem cells with miRNA-based strategies and particle radiation therapy"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:41:34.372736+00:00"}