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Redox Sensitive MR Contrast Agent
https://repo.qst.go.jp/records/70091
https://repo.qst.go.jp/records/7009101a374eb-c074-4ba8-b34d-c94553a0b8d4
| アイテムタイプ | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-05-10 | |||||
| タイトル | ||||||
| タイトル | Redox Sensitive MR Contrast Agent | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference output | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Kenichiro
× Matsumoto, Kenichiro× Nakanishi, Ikuo× Anzai, Kazunori× 松本 謙一郎× 中西 郁夫× 安西 和紀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Nitroxyl radicals (also known as nitroxide) have been used as <I>in vitro</I> and <I>in vivo</I> redox probes in fields of electron paramagnetic resonance (EPR) spectroscopy and imaging. Nitroxyl radicals are paramagnetic species, which also can be detected using T<SUB>1</SUB>-weighted MRI. Reactive oxygen species (ROS) react with nitroxyl radicals to lose paramagnetism. The time course of <I>in vivo</I> MRI intensity induced by a nitroxyl radical can give tissue redox information, which is the so called the redox imaging technique. Employing a membrane permeable nitroxyl radical, redox information in tissues could be available. A brief theory of redox imaging techniques and applications of redox imaging techniques are introduced. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Experimental Biology 2010 | |||||
| 発表年月日 | ||||||
| 日付 | 2010-04-28 | |||||
| 日付タイプ | Issued | |||||
