@misc{oai:repo.qst.go.jp:00070091, author = {Matsumoto, Kenichiro and Nakanishi, Ikuo and Anzai, Kazunori and 松本 謙一郎 and 中西 郁夫 and 安西 和紀}, month = {Apr}, note = {Nitroxyl radicals (also known as nitroxide) have been used as in vitro and in vivo redox probes in fields of electron paramagnetic resonance (EPR) spectroscopy and imaging. Nitroxyl radicals are paramagnetic species, which also can be detected using T1-weighted MRI. Reactive oxygen species (ROS) react with nitroxyl radicals to lose paramagnetism. The time course of in vivo MRI intensity induced by a nitroxyl radical can give tissue redox information, which is the so called the redox imaging technique. Employing a membrane permeable nitroxyl radical, redox information in tissues could be available. A brief theory of redox imaging techniques and applications of redox imaging techniques are introduced., Experimental Biology 2010}, title = {Redox Sensitive MR Contrast Agent}, year = {2010} }