WEKO3
アイテム
重粒子線誘発DNA 障害の特徴
https://repo.qst.go.jp/records/63775
https://repo.qst.go.jp/records/63775d6053282-2734-40d8-9b8a-f00c4bc723e5
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-02-05 | |||||
| タイトル | ||||||
| タイトル | 重粒子線誘発DNA 障害の特徴 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
吉田, 佳世
× 吉田, 佳世× 吉田, 周平× 江口−笠井, 清美× 森田, 隆× 吉田 佳世× 吉田 周平× 笠井 清美× 森田 隆 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In order to evaluate the effects of space radiation to germ line cells and embryos, we irradiated mouse ES cells and the sell survival and their development was examined. Mouse cultured and frozen ES cells (-80 degree in C) were irradiated by X-ray, Fe and C ion heavy particles. The cells were plated and numbers of colony were counted. The mouse ES cells were most sensitive to Fe ion particles at 0-1Gy of exposure and carbon gave moderate effect to ES cells. Interestingly, radiation at low dose of 0-1 Gy, by Fe and C particles damaged ES cells seriously, while X-ray did not We also examined phosphorylation of histone H2AX after irradiation of X-ray, Fe particles. The result showed that low doses of Fe, C particles induced phosphorylation of histone H2AX. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 平成２０年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究成果発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2009-04-14 | |||||
| 日付タイプ | Issued | |||||
