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炭素線治療効果の早期画像診断法の開発-基礎的研究-(18B253)
https://repo.qst.go.jp/records/55679
https://repo.qst.go.jp/records/556797d169ff0-e4ec-4a7b-a481-d505bb576c69
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2010-01-28 | |||||
タイトル | ||||||
タイトル | 炭素線治療効果の早期画像診断法の開発-基礎的研究-(18B253) | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
高井, 伸彦
× 高井, 伸彦× 鵜澤, 玲子× 平山, 亮一× 松本, 孔貴× 安藤, 興一× 小池, 幸子× 古澤, 佳也× その他× 高井 伸彦× 鵜澤 玲子× 平山 亮一× 松本 孔貴× 安藤 興一× 小池 幸子× 古澤 佳也 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | X-rays or gamma-rays in the physical and biological characteristics. On the other hand, radiation to abdominal cancer, for example the uterus and the bladder, would cause damages not only to the tumor but also to the gut nearby target still. Nuclear medicine imaging for diagnosis, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET), has been applied clinically for the diagnosis of cancer. Radiotracer is distributed in each organ by the blood flow. Nevertheless, it has not been established to evaluate tissue functions in consideration of the regional blood flow. Especially in irradiated tumors or normal tissues close to the tumor, the change of blood flow would be resulted from vascular necrosis by irradiation. Therefore, these changes should be taken account for an investigation of tracer accumulation. Tumor repopulation after carbon-ion irradiation was estimated using 14C-labeled thymidine as a tracer for the early response. We demonstrated that the [2-14C]thymidine uptake in vivo could be an appropriate marker for early tumor response to irradiation and correction by blood flow is essential for the evaluation by [2-14C]thymidine. |
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書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 巻 2009, p. 49-50, 発行日 2009-06 |
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出版者 | ||||||
出版者 | 放医研 |