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Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems
https://repo.qst.go.jp/records/47567
https://repo.qst.go.jp/records/4756763806c19-3d41-4e2a-a532-53add6f924cc
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-10-12 | |||||
| タイトル | ||||||
| タイトル | Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Molinelli, Silvia
× Molinelli, Silvia× Magro, Giuseppe× Mairani, Andrea× Matsufuji, Naruhiro× Kanematsu, Nobuyuki× Inaniwa, Taku× Mirandola, Alfredo× Russo, Stefania× Mastella, Edoardo× Hasegawa, Azusa× Tsuji, Hiroshi× Yamada, Shigeru× Vischioni, Barbara× Vitolo, Viviana× Ferrari, Alfredo× Ciocca, Mario× Kamada, Tadashi× Tsujii, Hirohiko× Orecchia, Roberto× Fossati, Piero× Ｍｏｌｉｎｅｌｌｉ Ｓｉｌｖｉａ× Ｍａｉｒａｎｉ Ａｎｄｒｅａ× 松藤 成弘× 兼松 伸幸× 稲庭 拓× 長谷川 安都佐× 辻 比呂志× 山田 滋× Ｖｉｓｃｈｉｏｎｉ Ｂａｒｂａｒａ× 鎌田 正× 辻井 博彦× Ｆｏｓｓａｔｉ Ｐｉｅｒｏ |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background and purpose In carbon ion radiotherapy (CIRT), the use of different relative biological effectiveness (RBE) models in the RBE-weighted dose (DRBE) calculation can lead to deviations in the physical dose (Dphy) delivered to the patient. Our aim is to reduce target Dphy deviations by converting prescription dose values. \nMaterial and methods Planning data of patients treated at the National Institute of Radiological Sciences (NIRS) were collected, with prescribed doses per fraction ranging from 3.6 Gy (RBE) to 4.6 Gy (RBE), according to the Japanese semi-empirical model. The Dphy was Monte Carlo (MC) re-calculated simulating the NIRS beamline. The local effect model (LEM)_I was then applied to estimate DRBE. Target median DRBE ratios between MC + LEM_I and NIRS plans determined correction factors for the conversion of prescription doses. Plans were re-optimized in a LEM_I-based commercial system, prescribing the NIRS uncorrected and corrected DRBE. \nResults The MC + LEM_I target median DRBE was respectively 15% and 5% higher than the NIRS reference, for the lowest and highest dose levels. Uncorrected DRBE prescription resulted in significantly lower target Dphy in re-optimized plans, with respect to NIRS plans. \nConclusions Prescription dose conversion factors could minimize target physical dose variations due to the use of different radiobiological models in the calculation of CIRT RBE-weighted dose. |
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| 書誌情報 |
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 巻 120, 号 2, p. 307-312, 発行日 2016-08 |
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| 出版者 | ||||||
| 出版者 | Elsevier Scientific Publishers | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0167-8140 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 27394694 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.radonc.2016.05.031 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.thegreenjournal.com/article/S0167-8140(16)31173-2/fulltext | |||||
| 関連名称 | http://www.thegreenjournal.com/article/S0167-8140(16)31173-2/fulltext | |||||
