{"created":"2023-05-15T14:36:54.931529+00:00","id":47567,"links":{},"metadata":{"_buckets":{"deposit":"47b6d4ce-5f89-4819-8a90-5c25735c4a92"},"_deposit":{"created_by":1,"id":"47567","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"47567"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00047567","sets":["1"]},"author_link":["476812","476807","476824","476818","476820","476811","476802","476825","476797","476814","476801","476819","476821","476826","476828","476809","476822","476804","476798","476805","476810","476808","476816","476803","476800","476799","476806","476815","476817","476823","476813","476827"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"312","bibliographicPageStart":"307","bibliographicVolumeNumber":"120","bibliographic_titles":[{"bibliographic_title":"Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and purpose\nIn carbon ion radiotherapy (CIRT), the use of different relative biological effectiveness (RBE) models in the RBE-weighted dose (DRBE) calculation can lead to deviations in the physical dose (Dphy) delivered to the patient. Our aim is to reduce target Dphy deviations by converting prescription dose values.\n\\nMaterial and methods\nPlanning data of patients treated at the National Institute of Radiological Sciences (NIRS) were collected, with prescribed doses per fraction ranging from 3.6 Gy (RBE) to 4.6 Gy (RBE), according to the Japanese semi-empirical model. The Dphy was Monte Carlo (MC) re-calculated simulating the NIRS beamline. The local effect model (LEM)_I was then applied to estimate DRBE. Target median DRBE ratios between MC + LEM_I and NIRS plans determined correction factors for the conversion of prescription doses. Plans were re-optimized in a LEM_I-based commercial system, prescribing the NIRS uncorrected and corrected DRBE.\n\\nResults\nThe MC + LEM_I target median DRBE was respectively 15% and 5% higher than the NIRS reference, for the lowest and highest dose levels. Uncorrected DRBE prescription resulted in significantly lower target Dphy in re-optimized plans, with respect to NIRS plans.\n\\nConclusions\nPrescription dose conversion factors could minimize target physical dose variations due to the use of different radiobiological models in the calculation of CIRT RBE-weighted dose.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Scientific Publishers"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"27394694","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.radonc.2016.05.031 ","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.thegreenjournal.com/article/S0167-8140(16)31173-2/fulltext"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.thegreenjournal.com/article/S0167-8140(16)31173-2/fulltext","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0167-8140 ","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Molinelli, Silvia"}],"nameIdentifiers":[{"nameIdentifier":"476797","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Magro, Giuseppe"}],"nameIdentifiers":[{"nameIdentifier":"476798","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mairani, Andrea"}],"nameIdentifiers":[{"nameIdentifier":"476799","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsufuji, Naruhiro"}],"nameIdentifiers":[{"nameIdentifier":"476800","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanematsu, Nobuyuki"}],"nameIdentifiers":[{"nameIdentifier":"476801","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inaniwa, Taku"}],"nameIdentifiers":[{"nameIdentifier":"476802","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mirandola, Alfredo"}],"nameIdentifiers":[{"nameIdentifier":"476803","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Russo, Stefania"}],"nameIdentifiers":[{"nameIdentifier":"476804","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mastella, Edoardo"}],"nameIdentifiers":[{"nameIdentifier":"476805","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hasegawa, Azusa"}],"nameIdentifiers":[{"nameIdentifier":"476806","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"476807","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Shigeru"}],"nameIdentifiers":[{"nameIdentifier":"476808","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Vischioni, Barbara"}],"nameIdentifiers":[{"nameIdentifier":"476809","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Vitolo, Viviana"}],"nameIdentifiers":[{"nameIdentifier":"476810","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ferrari, Alfredo"}],"nameIdentifiers":[{"nameIdentifier":"476811","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ciocca, Mario"}],"nameIdentifiers":[{"nameIdentifier":"476812","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"476813","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"476814","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Orecchia, Roberto"}],"nameIdentifiers":[{"nameIdentifier":"476815","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fossati, Piero"}],"nameIdentifiers":[{"nameIdentifier":"476816","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｍｏｌｉｎｅｌｌｉ Ｓｉｌｖｉａ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476817","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｍａｉｒａｎｉ Ａｎｄｒｅａ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476818","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松藤 成弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476819","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"兼松 伸幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476820","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"稲庭 拓","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476821","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476822","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 比呂志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476823","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 滋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476824","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｖｉｓｃｈｉｏｎｉ Ｂａｒｂａｒａ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476825","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476826","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476827","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｆｏｓｓａｔｉ Ｐｉｅｒｏ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"476828","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-12"},"publish_date":"2016-10-12","publish_status":"0","recid":"47567","relation_version_is_last":true,"title":["Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:38:15.284047+00:00"}