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Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection.
https://repo.qst.go.jp/records/47468
https://repo.qst.go.jp/records/4746859db7052-9e94-49bc-ba2b-c60815109ec5
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-08-10 | |||||
| タイトル | ||||||
| タイトル | Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suganami, Akiko
× Suganami, Akiko× Iwadate, Yasuo× Shibata, Sayaka× Yamashita, Masamichi× Tanaka, Tsutomu× Shinozaki, Natsuki× Aoki, Ichio× Saeki, Naokatsu× Shirasawa, Hiroshi× Okamoto, Yoshiharu× Tamura, Yutaka× 菅波 晃子× 岩立 康男× 柴田 さやか× 青木 伊知男× 田村 裕 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Some tumor-specific near-infrared (NIR) fluorescent dyes such as indocyanine green (ICG), IDRye800CW, and 5-aminolevulinic acid have been used clinically for detecting tumor margins or micro-cancer lesions. In this study, we evaluated the physicochemical properties of liposomally formulated phospholipid-conjugated ICG, denoted by LP-iDOPE, as a clinically translatable NIR imaging nanoparticle for brain tumors. We also confirmed its brain-tumor-specific biodistribution and its characteristics as the intra-operative NIR imaging nanoparticles for brain tumor surgery. These properties of LP-iDOPE may enable neurosurgeons to achieve more accurate identification and more complete resection of brain tumor. | |||||
| 書誌情報 |
International journal of pharmaceutics 巻 496, 号 2, p. 401-406, 発行日 2015-10 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0378-5173 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 26453781 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.ijpharm.2015.10.001 | |||||
