{"created":"2023-05-15T14:36:50.566600+00:00","id":47468,"links":{},"metadata":{"_buckets":{"deposit":"19de22f2-d32f-4cf1-88aa-98ceb97e4944"},"_deposit":{"created_by":1,"id":"47468","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"47468"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00047468","sets":["1"]},"author_link":["475558","475555","475550","475553","475552","475546","475556","475548","475554","475557","475559","475545","475551","475547","475544","475549"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"406","bibliographicPageStart":"401","bibliographicVolumeNumber":"496","bibliographic_titles":[{"bibliographic_title":"International journal of pharmaceutics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Some tumor-specific near-infrared (NIR) fluorescent dyes such as indocyanine green (ICG), IDRye800CW, and 5-aminolevulinic acid have been used clinically for detecting tumor margins or micro-cancer lesions. In this study, we evaluated the physicochemical properties of liposomally formulated phospholipid-conjugated ICG, denoted by LP-iDOPE, as a clinically translatable NIR imaging nanoparticle for brain tumors. We also confirmed its brain-tumor-specific biodistribution and its characteristics as the intra-operative NIR imaging nanoparticles for brain tumor surgery. These properties of LP-iDOPE may enable neurosurgeons to achieve more accurate identification and more complete resection of brain tumor.","subitem_description_type":"Abstract"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"26453781","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ijpharm.2015.10.001","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0378-5173","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suganami, Akiko"}],"nameIdentifiers":[{"nameIdentifier":"475544","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwadate, Yasuo"}],"nameIdentifiers":[{"nameIdentifier":"475545","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shibata, Sayaka"}],"nameIdentifiers":[{"nameIdentifier":"475546","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamashita, Masamichi"}],"nameIdentifiers":[{"nameIdentifier":"475547","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Tsutomu"}],"nameIdentifiers":[{"nameIdentifier":"475548","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shinozaki, Natsuki"}],"nameIdentifiers":[{"nameIdentifier":"475549","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoki, Ichio"}],"nameIdentifiers":[{"nameIdentifier":"475550","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saeki, Naokatsu"}],"nameIdentifiers":[{"nameIdentifier":"475551","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shirasawa, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"475552","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okamoto, Yoshiharu"}],"nameIdentifiers":[{"nameIdentifier":"475553","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tamura, Yutaka"}],"nameIdentifiers":[{"nameIdentifier":"475554","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅波 晃子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475555","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩立 康男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475556","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柴田 さやか","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475557","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青木 伊知男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475558","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田村 裕","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475559","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-10"},"publish_date":"2016-08-10","publish_status":"0","recid":"47468","relation_version_is_last":true,"title":["Liposomally formulated phospholipid-conjugated indocyanine green for intra-operative brain tumor detection and resection."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:39:28.250208+00:00"}