ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 原著論文

Radiation-Sensitising Effects of Antennapedia Proteins (ANTP)-SmacN7 on Tumour Cells

https://repo.qst.go.jp/records/46694
https://repo.qst.go.jp/records/46694
1a40cccf-89a4-4143-ac99-a8b843ad3d60
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-01-14
タイトル
タイトル Radiation-Sensitising Effects of Antennapedia Proteins (ANTP)-SmacN7 on Tumour Cells
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Li, Qing Du(杜 利清)

× Li, Qing Du(杜 利清)

WEKO 465581

Li, Qing Du(杜 利清)

Search repository
Yan, Wang(王 彦)

× Yan, Wang(王 彦)

WEKO 465582

Yan, Wang(王 彦)

Search repository
Chang, Xu(徐 暢)

× Chang, Xu(徐 暢)

WEKO 465583

Chang, Xu(徐 暢)

Search repository
Jia, Cao (曹 佳)

× Jia, Cao (曹 佳)

WEKO 465584

Jia, Cao (曹 佳)

Search repository
Qin, Wang (王 勤)

× Qin, Wang (王 勤)

WEKO 465585

Qin, Wang (王 勤)

Search repository
Hui, Zhao(趙 輝)

× Hui, Zhao(趙 輝)

WEKO 465586

Hui, Zhao(趙 輝)

Search repository
Fei-Yue, Fan(樊 飛躍)

× Fei-Yue, Fan(樊 飛躍)

WEKO 465587

Fei-Yue, Fan(樊 飛躍)

Search repository
王, 冰

× 王, 冰

WEKO 465588

王, 冰

Search repository
勝部, 孝則

× 勝部, 孝則

WEKO 465589

勝部, 孝則

Search repository
Sai, Jun Fan(樊 賽軍)

× Sai, Jun Fan(樊 賽軍)

WEKO 465590

Sai, Jun Fan(樊 賽軍)

Search repository
Qiang, Liu(劉 強)

× Qiang, Liu(劉 強)

WEKO 465591

Qiang, Liu(劉 強)

Search repository
王 冰

× 王 冰

WEKO 465592

en 王 冰

Search repository
勝部 孝則

× 勝部 孝則

WEKO 465593

en 勝部 孝則

Search repository
抄録
内容記述タイプ Abstract
内容記述 he objective of this study was to investigate the underlying mechanisms behind the radiation-sensitising effects of the antennapedia proteins (ANTP)-smacN7 fusion protein on tumour cells. ANTP-SmacN7 fusion proteins were synthesised, and the ability of this fusion protein to penetrate cells was observed. Effects of radiation on the expression of X-linked inhibitor of apoptosis protein (XIAP) were detected by western blotting. The radiation-sensitising effects of ANTP-SmacN7 fusion proteins were observed by a clonogenic assay. The effects of drugs and radiation on tumour cell apoptosis were determined using Annexin V/FITC double staining. Changes in caspase-8, caspase-9 and caspase-3 were detected by western blot before and after ANTP-SmacN7 inhibition of XIAP. The ANTP-SmacN7 fusion protein could enter and accumulate in cells; in vitro XIAP expression of radiation-induced tumour cells was negatively correlated with tumor radiosensitivity. The ANTP-SmacN7 fusion protein promoted tumour cell apoptosis through the activation of caspase3. ANTP-SmacN7 fusion protein may reduce tumour cell radioresistance by inducing caspase3 activation.
書誌情報 International Journal of Molecular Sciences.

巻 14, 号 12, p. 24087-24096, 発行日 2013-12
出版者
出版者 Multidisciplinary Digital Publishing Institute
DOI
識別子タイプ DOI
関連識別子 doi:10.3390/ijms141224087
戻る
0
views
See details
Views

Versions

Ver.1 2023-05-15 23:48:44.849673
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3