WEKO3
アイテム
{"_buckets": {"deposit": "4219897f-7ab4-4254-af16-2e2c4d5f8c16"}, "_deposit": {"created_by": 1, "id": "45160", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "45160"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00045160", "sets": ["1"]}, "author_link": ["448503", "448496", "448495", "448509", "448505", "448502", "448500", "448507", "448501", "448498", "448504", "448506", "448508", "448499", "448510", "448497"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "146", "bibliographicPageStart": "143", "bibliographicVolumeNumber": "22", "bibliographic_titles": [{"bibliographic_title": "Annals of Nuclear Medicine"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "In practical positron emission tomography(PET) diagnosis, a shortened protocol is preferred for patients with brain disorders. In this study, the applicability\nof a shortened protocol as an alternative to the 90-min PET scan with [11C]SA4503 for quantitative sigma1 receptor measurement was investigated. Tissue time-activity curves of 288 regions of interest in the brain from 32 [11C]SA4503-PET scans of 16 healthy subjects prior to and following administration of a selective serotonin reuptake inhibitor (fluvoxamine or paroxetine) were applied to two algorithms of quantitative analysis; binding potential (BP) was derived from compartmental\nanalysis based on nonlinear estimation, and total distribution volume (tDV) was derived from Logan plot analysis. \nAs a result, although both BP and tDV tended to be underestimated by the shortened method, the estimates from the shortened protocol had good linear relationships with those of the full-length protocol. In conclusion, if approximately 10% differences in the estimated results are acceptable for a specific purpose, then\na 60-min measurement protocol is capable of providing reliable results.", "subitem_description_type": "Abstract"}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/s12149-007-0088-x", "subitem_relation_type_select": "DOI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0914-7187", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sakata, Muneyuki"}], "nameIdentifiers": [{"nameIdentifier": "448495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura, Yuichi"}], "nameIdentifiers": [{"nameIdentifier": "448496", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Naganawa, Mika"}], "nameIdentifiers": [{"nameIdentifier": "448497", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishikawa, Masatomo"}], "nameIdentifiers": [{"nameIdentifier": "448498", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oda, Keiichi"}], "nameIdentifiers": [{"nameIdentifier": "448499", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishii, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "448500", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hashimoto, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "448501", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Chihara, Kunihiro"}], "nameIdentifiers": [{"nameIdentifier": "448502", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishiwata, Kiichi"}], "nameIdentifiers": [{"nameIdentifier": "448503", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "坂田 宗之", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448504", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "木村 裕一", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448505", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "長縄 美香", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448506", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "織田 圭一", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448507", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "石井 賢二", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448508", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "橋本 謙二", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448509", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "石渡 喜一", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "448510", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Shortened protocol in practical [11C] SA4503-PET studies for the sigma1 receptor quantification", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Shortened protocol in practical [11C] SA4503-PET studies for the sigma1 receptor quantification"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/45160", "pubdate": {"attribute_name": "公開日", "attribute_value": "2008-05-16"}, "publish_date": "2008-05-16", "publish_status": "0", "recid": "45160", "relation": {}, "relation_version_is_last": true, "title": ["Shortened protocol in practical [11C] SA4503-PET studies for the sigma1 receptor quantification"], "weko_shared_id": -1}
Shortened protocol in practical [11C] SA4503-PET studies for the sigma1 receptor quantification
https://repo.qst.go.jp/records/45160
https://repo.qst.go.jp/records/45160e2895604-e5b7-40b8-89a0-2310a3090f27
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2008-05-16 | |||||
タイトル | ||||||
タイトル | Shortened protocol in practical [11C] SA4503-PET studies for the sigma1 receptor quantification | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Sakata, Muneyuki
× Sakata, Muneyuki× Kimura, Yuichi× Naganawa, Mika× Ishikawa, Masatomo× Oda, Keiichi× Ishii, Kenji× Hashimoto, Kenji× Chihara, Kunihiro× Ishiwata, Kiichi× 坂田 宗之× 木村 裕一× 長縄 美香× 織田 圭一× 石井 賢二× 橋本 謙二× 石渡 喜一 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In practical positron emission tomography(PET) diagnosis, a shortened protocol is preferred for patients with brain disorders. In this study, the applicability of a shortened protocol as an alternative to the 90-min PET scan with [11C]SA4503 for quantitative sigma1 receptor measurement was investigated. Tissue time-activity curves of 288 regions of interest in the brain from 32 [11C]SA4503-PET scans of 16 healthy subjects prior to and following administration of a selective serotonin reuptake inhibitor (fluvoxamine or paroxetine) were applied to two algorithms of quantitative analysis; binding potential (BP) was derived from compartmental analysis based on nonlinear estimation, and total distribution volume (tDV) was derived from Logan plot analysis. As a result, although both BP and tDV tended to be underestimated by the shortened method, the estimates from the shortened protocol had good linear relationships with those of the full-length protocol. In conclusion, if approximately 10% differences in the estimated results are acceptable for a specific purpose, then a 60-min measurement protocol is capable of providing reliable results. |
|||||
書誌情報 |
Annals of Nuclear Medicine 巻 22, 号 2, p. 143-146, 発行日 2008-03 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0914-7187 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s12149-007-0088-x |