{"created":"2023-05-15T14:34:56.712218+00:00","id":45160,"links":{},"metadata":{"_buckets":{"deposit":"4219897f-7ab4-4254-af16-2e2c4d5f8c16"},"_deposit":{"created_by":1,"id":"45160","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45160"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045160","sets":["1"]},"author_link":["448503","448496","448495","448509","448505","448502","448500","448507","448501","448498","448504","448506","448508","448499","448510","448497"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"146","bibliographicPageStart":"143","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"Annals of Nuclear Medicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In practical positron emission tomography(PET) diagnosis, a shortened protocol is preferred for patients with brain disorders. In this study, the applicability\nof a shortened protocol as an alternative to the 90-min PET scan with [11C]SA4503 for quantitative sigma1 receptor measurement was investigated. Tissue time-activity curves of 288 regions of interest in the brain from 32 [11C]SA4503-PET scans of 16 healthy subjects prior to and following administration of a selective serotonin reuptake inhibitor (fluvoxamine or paroxetine) were applied to two algorithms of quantitative analysis; binding potential (BP) was derived from compartmental\nanalysis based on nonlinear estimation, and total distribution volume (tDV) was derived from Logan plot analysis. \nAs a result, although both BP and tDV tended to be underestimated by the shortened method, the estimates from the shortened protocol had good linear relationships with those of the full-length protocol. In conclusion, if approximately 10% differences in the estimated results are acceptable for a specific purpose, then\na 60-min measurement protocol is capable of providing reliable results.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12149-007-0088-x","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-7187","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakata, Muneyuki"}],"nameIdentifiers":[{"nameIdentifier":"448495","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"448496","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naganawa, Mika"}],"nameIdentifiers":[{"nameIdentifier":"448497","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Masatomo"}],"nameIdentifiers":[{"nameIdentifier":"448498","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oda, Keiichi"}],"nameIdentifiers":[{"nameIdentifier":"448499","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishii, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"448500","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hashimoto, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"448501","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Chihara, Kunihiro"}],"nameIdentifiers":[{"nameIdentifier":"448502","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishiwata, Kiichi"}],"nameIdentifiers":[{"nameIdentifier":"448503","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂田 宗之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448504","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村 裕一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448505","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長縄 美香","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448506","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"織田 圭一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448507","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石井 賢二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448508","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"橋本 謙二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448509","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石渡 喜一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448510","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Shortened protocol in practical [11C] SA4503-PET studies for the sigma1  receptor quantification","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Shortened protocol in practical [11C] SA4503-PET studies for the sigma1  receptor quantification"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-05-16"},"publish_date":"2008-05-16","publish_status":"0","recid":"45160","relation_version_is_last":true,"title":["Shortened protocol in practical [11C] SA4503-PET studies for the sigma1  receptor quantification"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:06:57.733171+00:00"}