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CLS-PET: a high-resolution portable small-animal PET with a 20 cm axial FOV
https://repo.qst.go.jp/records/86014
https://repo.qst.go.jp/records/86014c759f925-ae97-4b61-858e-b772005013d5
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-04-07 | |||||
| タイトル | ||||||
| タイトル | CLS-PET: a high-resolution portable small-animal PET with a 20 cm axial FOV | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Go, Akamatsu
× Go, Akamatsu× Eiji, Yoshida× Hideaki, Tashima× Shigeki, Ito× Yuma, Iwao× Hidekatsu, Wakizaka× Miwako, Takahashi× Taiga, Yamaya× Go, Akamatsu× Eiji, Yoshida× Hideaki, Tashima× Shigeki, Ito× Yuma, Iwao× Hidekatsu, Wakizaka× Miwako, Takahashi× Taiga, Yamaya |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Purpose] The crosshair light sharing (CLS) PET detector, which has depth-of-interaction (DOI) capability, was recently developed by our group. In this work, as the first practical system based on the CLS detector, we developed a high-resolution portable small-animal PET with a long axial field-of-view (FOV) of 20 cm. [Methods] The system was composed of 128 CLS detectors*, which consisted of GFAG crystals and SiPMs. All devices were mounted on a compact pushcart (740 mm × 950 mm), and the system worked with a power supply from a typical wall socket of AC100V. The axial FOV was 207 mm, which covered a total-body of rat. Performance characterization was performed according to the NEMA NU4 standards. In addition, a 22Na ultra-micro hot phantom was used for spatial resolution measurement, and normal mouse and rat PET imaging with 18F-NaF and 18F-FDG was performed for imaging demonstration. [Results] The developed CLS-PET system successfully resolved 0.75 mm rods of the ultra-micro hot phantom. The sensitivity was 1.1% at the FOV center and the peak noise-equivalent count rate was 62 kcps@76 kBq/mL. The coincidence timing resolution was 496 ps. For the NaF-PET, mouse and rat total-body images were obtained, and detailed bone structures were clearly observed. For the mouse FDG-PET, cardiac FDG uptakes were clearly visualized. [Conclusion] The CLS-PET system achieved sub-mm spatial resolution and successfully provided mouse and rat total-body images. This portable small-animal PET system can offer opportunities for novel applications such as studies on PET-guided radiation therapy and PET-guided surgery. *Yoshida, et al. Phys Med Biol. 2021;66:065013. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第123回日本医学物理学会学術大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2022-04-17 | |||||
| 日付タイプ | Issued | |||||
