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Single caudate neurons encode temporally discounted value for formulating motivation for action.
https://repo.qst.go.jp/records/84085
https://repo.qst.go.jp/records/840854c773872-262d-4b60-ab9b-f4473c1012f4
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-08-10 | |||||
| タイトル | ||||||
| タイトル | Single caudate neurons encode temporally discounted value for formulating motivation for action. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Hori, Yukiko
× Hori, Yukiko× Mimura, Koki× Nagai, Yuji× Fujimoto, Atsushi× Oyama, Kei× Kikuchi, Erika× Ken-Ichi, Inoue× Takada, Masahiko× Suhara, Tetsuya× J Richmond, Barry× Minamimoto, Takafumi× Yukiko, Hori× Koki, Mimura× Yuji, Nagai× Atsushi, Fujimoto× Kei, Oyama× Erika, Kikuchi× Tetsuya, Suhara× Takafumi, Minamimoto |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The term 'temporal discounting' describes both choice preferences and motivation for delayed rewards. Here we show that neuronal activity in the dorsal part of the primate caudate head (dCDh) signals the temporally discounted value needed to compute the motivation for delayed rewards. Macaque monkeys performed an instrumental task, in which visual cues indicated the forthcoming size and delay duration before reward. Single dCDh neurons represented the temporally discounted value without reflecting changes in the animal's physiological state. Bilateral pharmacological or chemogenetic inactivation of dCDh markedly distorted the normal task performance based on the integration of reward size and delay, but did not affect the task performance for different reward sizes without delay. These results suggest that dCDh is involved in encoding the integrated multidimensional information critical for motivation. | |||||
| 書誌情報 |
eLife 巻 10, p. e61248, 発行日 2021-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2050-084X | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 34328413 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.7554/eLife.61248 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://elifesciences.org/articles/61248 | |||||
