@article{oai:repo.qst.go.jp:00084085,
 author = {Hori, Yukiko and Mimura, Koki and Nagai, Yuji and Fujimoto, Atsushi and Oyama, Kei and Kikuchi, Erika and Ken-Ichi, Inoue and Takada, Masahiko and Suhara, Tetsuya and J Richmond, Barry and Minamimoto, Takafumi and Yukiko, Hori and Koki, Mimura and Yuji, Nagai and Atsushi, Fujimoto and Kei, Oyama and Erika, Kikuchi and Tetsuya, Suhara and Takafumi, Minamimoto},
 journal = {eLife},
 month = {Jul},
 note = {The term 'temporal discounting' describes both choice preferences and motivation for delayed rewards. Here we show that neuronal activity in the dorsal part of the primate caudate head (dCDh) signals the temporally discounted value needed to compute the motivation for delayed rewards. Macaque monkeys performed an instrumental task, in which visual cues indicated the forthcoming size and delay duration before reward. Single dCDh neurons represented the temporally discounted value without reflecting changes in the animal's physiological state. Bilateral pharmacological or chemogenetic inactivation of dCDh markedly distorted the normal task performance based on the integration of reward size and delay, but did not affect the task performance for different reward sizes without delay. These results suggest that dCDh is involved in encoding the integrated multidimensional information critical for motivation.},
 title = {Single caudate neurons encode temporally discounted value for formulating motivation for action.},
 volume = {10},
 year = {2021}
}