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Lung cancer risk in mice after low-dose-rate irradiation
https://repo.qst.go.jp/records/83580
https://repo.qst.go.jp/records/835803e49dbd1-4712-4e5c-9cee-725afdc0fd71
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-09-17 | |||||
| タイトル | ||||||
| タイトル | Lung cancer risk in mice after low-dose-rate irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kenshi, Suzuki
× Kenshi, Suzuki× Kazuhiro, Daino× Takamitsu, Morioka× Shizuko, Kakinuma× Kenshi, Suzuki× Kazuhiro, Daino× Takamitsu, Morioka× Shizuko, Kakinuma |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Especially, after the accident at TEPCO's Fukushima Daiichi Nuclear Power Station, there are concerns about cancer risks due to low-dose radiation exposure. However, since the risk is overwhelmingly smaller than the risk due to lifestyle-related factors such as smoking, it is difficult to accurately evaluate it by an epidemiological method in which bias tends to be a problem. Therefore, the purpose of this study is to analyze the risk of lung cancer by low-dose-rate radiation. In this study, we initially analyzed the risk of lung cancers in B3C3F1 mice irradiated with gamma-rays at high-dose-rate (30 Gy/hour, total doses of 200 mGy to 4 Gy). A dose-dependent increase in the incidence of lung adenocarcinoma was observed. Interestingly, by pathological analysis, we found frequent occurrence of nuclear grooves (one of the nuclear atypia) in lung cancer cells from gamma-irradiated group compared with that of non-irradiated group. Currently, we are analyzing the risk for lung cancers in mice irradiated with low dose rate (6 mGy/hour) of gamma-rays. These results will be presented at the conference. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第64回日本放射線影響学会 | |||||
| 発表年月日 | ||||||
| 日付 | 2021-09-22 | |||||
| 日付タイプ | Issued | |||||
