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99mTc-GSAシンチグラフィによる肝腫瘍重粒子線治療後患者の肝予備能評価
https://repo.qst.go.jp/records/82904
https://repo.qst.go.jp/records/829042a52f890-ec9e-4e60-8fb2-73bc06590277
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-06-01 | |||||
| タイトル | ||||||
| タイトル | 99mTc-GSAシンチグラフィによる肝腫瘍重粒子線治療後患者の肝予備能評価 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
山崎, 香奈
× 山崎, 香奈× 西井, 龍一× 牧島, 弘和× 金子, 崇× 水谷, 陽一× 田村, 謙太郎× 東, 達也× 辻, 比呂志× Kana, Yamazaki× Ryuichi, Nishii× Hirokazu, Makishima× Takashi, Kaneko× Kentaro, Tamura× Tatsuya, Higashi× Hiroshi, Tsuji |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Objective] 99mTc-GSA scintigraphy is performed for patients before and after carbon-ion radiotherapy (CIRT) for liver tumors in our hospital. It is essential to assess liver reserve capacity and follow-up post-CIRT value for the long term. In this study, we evaluated the usefulness of 99mTc-GSA dynamic scintigraphy for the follow-up assessment of liver reserve capacity in patients before and after CIRT. [Materials and Methods] Eleven patients who received 99mTc-GSA scintigraphy imaging before CIRT, and twice during 3-18 months after CIRT were enrolled in this investigation. After intravenous injection of 99mTc-GSA, dynamic and SPECT imaging were performed using a gamma camera. The maximal GSA removal rate (GSA-Rmax), GSA-Rmax of the predicted residual liver after CIRT (GSA-RL) were calculated by applying 99mTc-GSA dynamics of heart and liver to a five-compartment model. GSA-Rmax was followed before CIRT and twice after CIRT. [Results] GSA-RL before CIRT and GSA-Rmax of first post-CIRT (3-12 months after CIRT), GSA-Rmax of second post-CIRT (6-18 months after CIRT) were 0.45 ± 0.17, 0.38 ± 0.12, 0.44 ± 0.16 mg/min, respectively (n.s.). The residual liver reserve after first and second post-CIRT may reflect long-term liver reserve. [Conclusion] 99mTc-GSA scintigraphy was useful for the follow-up assessment of liver reserve capacity in patients before and after CIRT for liver tumors. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第80回日本医学放射線学会総会 | |||||
| 発表年月日 | ||||||
| 日付 | 2021-04-15 | |||||
| 日付タイプ | Issued | |||||
