@misc{oai:repo.qst.go.jp:00082904,
 author = {山崎, 香奈 and 西井, 龍一 and 牧島, 弘和 and 金子, 崇 and 水谷, 陽一 and 田村, 謙太郎 and 東, 達也 and 辻, 比呂志 and Kana, Yamazaki and Ryuichi, Nishii and Hirokazu, Makishima and Takashi, Kaneko and Kentaro, Tamura and Tatsuya, Higashi and Hiroshi, Tsuji},
 month = {Apr},
 note = {[Objective]
99mTc-GSA scintigraphy is performed for patients before and after carbon-ion radiotherapy (CIRT) for liver tumors in our hospital. It is essential to assess liver reserve capacity and follow-up post-CIRT value for the long term. In this study, we evaluated the usefulness of 99mTc-GSA dynamic scintigraphy for the follow-up assessment of liver reserve capacity in patients before and after CIRT.
[Materials and Methods]
Eleven patients who received 99mTc-GSA scintigraphy imaging before CIRT, and twice during 3-18 months after CIRT were enrolled in this investigation. After intravenous injection of 99mTc-GSA, dynamic and SPECT imaging were performed using a gamma camera. The maximal GSA removal rate (GSA-Rmax), GSA-Rmax of the predicted residual liver after CIRT (GSA-RL) were calculated by applying 99mTc-GSA dynamics of heart and liver to a five-compartment model. GSA-Rmax was followed before CIRT and twice after CIRT. 
[Results]
GSA-RL before CIRT and GSA-Rmax of first post-CIRT (3-12 months after CIRT), GSA-Rmax of second post-CIRT (6-18 months after CIRT) were 0.45 ± 0.17, 0.38 ± 0.12, 0.44 ± 0.16 mg/min, respectively (n.s.). The residual liver reserve after first and second post-CIRT may reflect long-term liver reserve.
[Conclusion] 
99mTc-GSA scintigraphy was useful for the follow-up assessment of liver reserve capacity in patients before and after CIRT for liver tumors., 第80回日本医学放射線学会総会},
 title = {99mTc-GSAシンチグラフィによる肝腫瘍重粒子線治療後患者の肝予備能評価},
 year = {2021}
}