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Evaluation of the Cooling Effect by He Gas for the Production of At-211 with a Bi plate
https://repo.qst.go.jp/records/82622
https://repo.qst.go.jp/records/8262242fcd40f-7fd9-4321-b69e-ec56c5423bb8
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-04-05 | |||||
| タイトル | ||||||
| タイトル | Evaluation of the Cooling Effect by He Gas for the Production of At-211 with a Bi plate | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shigeki, Watanabe
× Shigeki, Watanabe× Masashi, Koka (Beam Operation)× Enomoto, Kazuyuki× Nobumasa, Miyawaki× Tetsuya, Sakashita× Ichiro, Sasaki× Noriko, Ishioka× Shigeki, Watanabe× Enomoto, Kazuyuki× Nobumasa, Miyawaki× Tetsuya, Sakashita× Ichiro, Sasaki× Noriko, Ishioka |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Astatine-211 is one of the promising alpha-emitting radionuclides for the targeted alpha therapy (TAT), internal radiotherapy using alpha-emitting radioisotopes. At-211 is basically produced by irradiating He beams with 28–29 MeV to a bismuth (Bi) target. Irradiations with high beam current (µA order) are necessary to produce At-211 for preclinical and clinical studies because they require its radioactivity on the order of subGBq to GBq. Low melting point of Bi (273.1°C) often causes melting of the Bi during irradiation with high beam current. The aim of this study is therefore to optimize irradiation condition without observing Bi melting. | |||||
| 書誌情報 |
QST Takasaki Annual Report 2019 p. 105, 発行日 2021-03 |
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