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SOG1 homologues regulate DNA-damage responses in Physcomitrella patens.
https://repo.qst.go.jp/records/82352
https://repo.qst.go.jp/records/82352678526a8-c539-4669-99d0-c96cd958505c
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-03-22 | |||||
| タイトル | ||||||
| タイトル | SOG1 homologues regulate DNA-damage responses in Physcomitrella patens. | |||||
| タイトル | ||||||
| タイトル | SOG1ホモログはヒメツリガネゴケのDNA損傷応答を制御する | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Sakamoto, Ayako
× Sakamoto, Ayako× Sakamoto, Tomoaki× Yokota, Yuuichiro× Teranishi , Mika× kimura, Seisuke× Ayako, Sakamoto× Yuuichiro, Yokota |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A NAC-type transcription factor SUPPRESSOR OF GAMMA RESPONSE 1 (SOG1), found in seed plants, is a master regulator for DNA damage responses (DDR). Upon DNA damage, SOG1 is phosphorylated by the ATM, a conserved Ser/Thr kinase in both animal and plant kingdoms. Then it regulates the expression of a large number of downstream DDR genes. To know the origin of DDR network in land plants, we searched for a homologue(s) of SOG1 in a moss Physcomitrella patens and identified PpSOG1a and PpSOG1b. To assess if either of them, or both, function(s) in DDR, we established knockout plant lines via CRISPR/Cas9 gene editing. Although neither sog1a nor sog1b single mutant showed obviously notable phenotypes, the double knockout sog1a sog1b plants showed reduced expression of DNA-repair genes after gamma-irradiation. The double mutant also showed resistance to several DNA-damaging treatments as similarly seen in Arabidopsis sog1 plants. These results suggest that PpSOG1a and PpSOG1b work redundantly on DDR response in P. patens, and also that the plant specific DDR system had been established prior to the emerging of vascular plants. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第62回日本植物生理学会年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2021-03-14 | |||||
| 日付タイプ | Issued | |||||
