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口腔非扁平上皮癌に対する重粒子線治療の安全性・有効性の検討
https://repo.qst.go.jp/records/82040
https://repo.qst.go.jp/records/82040b137f5d9-97fd-45a3-a98a-62d122a61b18
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-03-02 | |||||
| タイトル | ||||||
| タイトル | 口腔非扁平上皮癌に対する重粒子線治療の安全性・有効性の検討 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
伊川, 裕明
× 伊川, 裕明× 小藤, 昌志× 林, 和彦× 外木, 守雄× 高木, 亮× 野村, 武史× 辻, 比呂志× 鎌田, 正× Hiroaki, Ikawa× Masashi, Koto× Kazuhiko, Hayashi× Morio, Tonogi× Ryo, Takagi× Hiroshi, Tsuji× Tadashi, Kamada |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract: Background: This study evaluated carbon-ion radiotherapy (C-ion RT) for oral non-squamous cell carcmomas. Methods: We retrospectively obtained data from 74 patients who underwent C-ion RT for oral malignancies between April 1997 and March 2016. The C-ion RT was administered in 16 fractions at a total dose of 57.6 Gy or 64.0 Gy (relative biological effectiveness). Results: Forty-three patients had salivary gland carcinomas, 29 patients had mucosal melanoma, and 2 patients had other types of pathologies. The tumors were classified as Tl-T3 (24 cases), T4a (21 cases), or T4b (29 cases). The median follow-up was 49 months. The 5-year rates were 78.8% for local control, 36.2% for progression-free survival, and 58.3% for overall survival. Although 10 patients developed grade 3 osteoradionecrosis after C-ion RT, all patients maintained their mastication and deglutition functions after sequestrectomy and prosthesis placement. Conclusion: C-ion RT was effective for oral non-squamous cell carcinomas and had acceptable toxicities. |
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| 書誌情報 |
日本口腔外科学会雑誌 巻 67, 号 2, p. 100-108, 発行日 2021-02 |
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| 出版者 | ||||||
| 出版者 | 日本口腔外科学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00215163 | |||||
