@article{oai:repo.qst.go.jp:00082040,
 author = {伊川, 裕明 and 小藤, 昌志 and 林, 和彦 and 外木, 守雄 and 高木, 亮 and 野村, 武史 and 辻, 比呂志 and 鎌田, 正 and Hiroaki, Ikawa and Masashi, Koto and Kazuhiko, Hayashi and Morio, Tonogi and Ryo, Takagi and Hiroshi, Tsuji and Tadashi, Kamada},
 issue = {2},
 journal = {日本口腔外科学会雑誌},
 month = {Feb},
 note = {Abstract:
Background: This study evaluated carbon-ion radiotherapy (C-ion RT) for oral non-squamous cell carcmomas.
Methods: We retrospectively obtained data from 74 patients who underwent C-ion RT for oral malignancies between April 1997 and March 2016. The C-ion RT was administered in 16 fractions at a total dose of 57.6 Gy or
64.0 Gy (relative biological effectiveness).
Results: Forty-three patients had salivary gland carcinomas, 29 patients had mucosal melanoma, and 2 patients had other types of pathologies. The tumors were classified as Tl-T3  (24 cases), T4a  (21 cases), or T4b (29 cases). The median follow-up was 49 months. The 5-year rates were 78.8% for local control, 36.2% for progression-free survival, and 58.3% for overall survival. Although 10 patients developed grade 3 osteoradionecrosis after C-ion RT, all patients maintained their mastication and deglutition functions after sequestrectomy and prosthesis placement.
Conclusion: C-ion RT was effective for oral non-squamous cell carcinomas and had acceptable toxicities.},
 pages = {100--108},
 title = {口腔非扁平上皮癌に対する重粒子線治療の安全性・有効性の検討},
 volume = {67},
 year = {2021}
}