{"_buckets": {"deposit": "95746723-0f99-4f5a-b416-c2b3b71a78bc"}, "_deposit": {"created_by": 1, "id": "81794", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "81794"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00081794", "sets": ["1"]}, "author_link": ["1010508", "1010503", "1010509", "1010505", "1010497", "1010494", "1010496", "1010493", "1010489", "1010495", "1010504", "1010498", "1010499", "1010506", "1010491", "1010501", "1010500", "1010502", "1010490", "1010507", "1010492"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2021-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "510", "bibliographicPageStart": "502", "bibliographicVolumeNumber": "62", "bibliographic_titles": [{"bibliographic_title": "Journal of radiation research"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The aim of this study was to assess the feasibility of planning dose-volume histogram (DVH) parameters in computed tomography-based 3D image-guided brachytherapy for locally advanced cervical cancer. In a prospective multi-institutional study, 60 patients with stage IIA2-IVA cervical cancer from eight institutions were treated with external beam radiotherapy using central shielding and intracavitary or hybrid (combined intracavitary/interstitial) brachytherapy (HBT). The dose constraints were set as a cumulative linear quadratic equivalent dose (EQD2) of at least 60 Gy for high-risk clinical target volume (HR-CTV) D90, D2cc ≤ 75 Gy for rectum, D2cc ≤ 90 Gy for bladder and D2cc ≤ 75 Gy for sigmoid. The median HR-CTV D90 was 70.0 Gy (range, 62.8-83.7 Gy) in EQD2. The median D2cc of rectum, bladder and sigmoid was 57.1 Gy (range, 39.8-72.1 Gy), 68.9 Gy (range, 46.5-84.9 Gy) and 57.2 Gy (range, 39.2-71.2 Gy) in EQD2, respectively. In 76 of 233 sessions (33%), 23 patients underwent HBT, and the median number of interstitial needles was 2 (range, 1-5). HBT for a bulky HR-CTV (≥40 cm3) significantly improved the HR-CTV D90 compared with intracavitary brachytherapy alone (P = 0.010). All patients fulfilled the dose constrains for target and at risk organs by undergoing HBT in one-third of sessions. We conclude that the planning DVH parameters used in our protocol are clinically feasible. ", "subitem_description_type": "Abstract"}]}, "item_8_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press"}]}, "item_8_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "  33532828", "subitem_relation_type_select": "PMID"}}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1093/jrr/rraa138", "subitem_relation_type_select": "DOI"}}]}, "item_8_relation_17": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://academic.oup.com/jrr/article/62/3/502/6126961", "subitem_relation_type_select": "URI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1349-9157", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": 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Noda"}], "nameIdentifiers": [{"nameIdentifier": "1010494", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murofushi, Keiko"}], "nameIdentifiers": [{"nameIdentifier": "1010495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ushijima, Hiroki"}], "nameIdentifiers": [{"nameIdentifier": "1010496", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Daisaku, Yoshida"}], "nameIdentifiers": [{"nameIdentifier": "1010497", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Noriyuki, Okonogi"}], "nameIdentifiers": [{"nameIdentifier": "1010498", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Isohashi, Fumiaki"}], "nameIdentifiers": [{"nameIdentifier": "1010499", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Masaru, Wakatsuki"}], "nameIdentifiers": [{"nameIdentifier": "1010500", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takashi, Nakano"}], 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tomography-based image-guided brachytherapy in locally advanced cervical cancer: a Japanese prospective multi-institutional study "}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/81794", "pubdate": {"attribute_name": "公開日", "attribute_value": "2021-02-08"}, "publish_date": "2021-02-08", "publish_status": "0", "recid": "81794", "relation": {}, "relation_version_is_last": true, "title": ["Dosimetric feasibility of computed tomography-based image-guided brachytherapy in locally advanced cervical cancer: a Japanese prospective multi-institutional study "], "weko_shared_id": -1}