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Micro-Slit X-Ray Irradiation Reveals Testicular Tissue-Sparing Effects: An Attempt at High-Precision Radiotherapy for Male Fertility Preservation

https://repo.qst.go.jp/records/80934
https://repo.qst.go.jp/records/80934
7919ca5f-ba87-40e3-a2b0-0281b2f84e26
Item type 一般雑誌記事 / Article(1)
公開日 2020-11-11
タイトル
タイトル Micro-Slit X-Ray Irradiation Reveals Testicular Tissue-Sparing Effects: An Attempt at High-Precision Radiotherapy for Male Fertility Preservation
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Fukunaga, H.

× Fukunaga, H.

WEKO 900171

Fukunaga, H.

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Prise, K.M.

× Prise, K.M.

WEKO 900172

Prise, K.M.

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Yokoya, A.

× Yokoya, A.

WEKO 900173

Yokoya, A.

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Yokoya, Akinari

× Yokoya, Akinari

WEKO 900174

en Yokoya, Akinari

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内容記述タイプ Abstract
内容記述 The preservation of male fertility during or after radiotherapy has long been desired to improve the quality of life for cancer survivors during their reproductive years. To approach this clinical issue, we focused on the tissue-sparing effect (TSE) in the testes in response to microbeam radiotherapy (MRT). In this study, we used ex vivo testicular tissue cultures obtained from Acr-GFP transgenic mice and revealed, for the first time, the significant TSE of high-precision MRT for maintaining spermatogenesis using live-tissue fluorescence imaging. This suggests that MRT is a promising approach for preserving male fertility.
書誌情報 Photon Factory Highlights 2019

p. 54-55, 発行日 2020-11
関連サイト
識別子タイプ URI
関連識別子 https://www2.kek.jp/imss/pf/science/publ/pfhl/2019/19hl4_7.pdf
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