@article{oai:repo.qst.go.jp:00080934, author = {Fukunaga, H. and Prise, K.M. and Yokoya, A. and Yokoya, Akinari}, journal = {Photon Factory Highlights 2019}, month = {Nov}, note = {The preservation of male fertility during or after radiotherapy has long been desired to improve the quality of life for cancer survivors during their reproductive years. To approach this clinical issue, we focused on the tissue-sparing effect (TSE) in the testes in response to microbeam radiotherapy (MRT). In this study, we used ex vivo testicular tissue cultures obtained from Acr-GFP transgenic mice and revealed, for the first time, the significant TSE of high-precision MRT for maintaining spermatogenesis using live-tissue fluorescence imaging. This suggests that MRT is a promising approach for preserving male fertility.}, pages = {54--55}, title = {Micro-Slit X-Ray Irradiation Reveals Testicular Tissue-Sparing Effects: An Attempt at High-Precision Radiotherapy for Male Fertility Preservation}, year = {2020} }