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A simple method for production of hydrophilic, rigid, and sterilized multi-layer 3D integrated polydimethylsiloxane microfluidic chips
https://repo.qst.go.jp/records/80126
https://repo.qst.go.jp/records/80126c414c6f7-0f47-4979-9647-b548c3181e83
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-05-25 | |||||
| タイトル | ||||||
| タイトル | A simple method for production of hydrophilic, rigid, and sterilized multi-layer 3D integrated polydimethylsiloxane microfluidic chips | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Oyama, Tomoko
× Oyama, Tomoko× Oyama, Kotaro× Taguchi, Mitsumasa× Oyama, Tomoko× Oyama, Kotaro× Taguchi, Mitsumasa |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Polydimethylsiloxane (PDMS) has many desirable features for microfluidics applications, but its hydrophobicity, the lack of a practical method for bonding PDMS layers, and unwanted deformation during use limit its use. We report a simple method for solving these problems simultaneously; by applying EB or γ-ray irradiation to stacked PDMS layers, we can not only bond the interfaces between the layers but also achieve long-lasting hydrophilization and sterilization of the internal microchannels and chambers, prevent nonspecific adsorption and absorption of hydrophobic small molecules, and enhance the mechanical strength of the material though crosslinking. This method is applicable in the mass production of 3D integrated PDMS microfluidic chips with some glass-like properties as well as for 3D structures with complex shapes that are difficult to fabricate with plastic or glass. | |||||
| 書誌情報 |
Lab on a Chip 巻 20, 号 13, p. 2354-2363, 発行日 2020-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1473-0189 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1039/D0LC00316F | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://pubs.rsc.org/en/content/articlelanding/2020/LC/D0LC00316F#!divAbstract | |||||
