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111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis.
https://repo.qst.go.jp/records/77706
https://repo.qst.go.jp/records/777066c033329-5851-4bef-b31c-8b6eddfcf1b0
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-10-15 | |||||
| タイトル | ||||||
| タイトル | 111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Fujiwara, Kentaro
× Fujiwara, Kentaro× B Tsuji, Atsushi× Sudo, Hitomi× Sugyo, Aya× Akiba, Hiroki× Iwanari, Hiroko× Osamu, Kusano-Arai× Tsumoto, Kouhei× Momose, Toshimitsu× Hamakubo, Takao× Higashi, Tatsuya× Kentaro, Fujiwara× Atsushi, Tsuji× Hitomi, Sudo× Aya, Sugyo× Tatsuya, Higashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Cadherin-17 (CDH17) is a transmembrane protein that mediates cell-cell adhesion and is frequently expressed in adenocarcinomas, including gastric cancer. CDH17 may be an effective diagnostic marker for the staging of gastric cancer. Here, we developed an In-labeled anti-CDH17 monoclonal antibody (Mab) as an imaging tracer and performed biodistribution and single-photon emission computed tomography (SPECT)/computed tomography (CT) imaging studies using mice with CDH17-positive gastric cancer xenografts. CDH17 expression in gastric cancer specimens was also analyzed. | |||||
| 書誌情報 |
Annals of nuclear medicine 巻 34, 号 1, p. 13-23, 発行日 2020-01 |
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| 出版者 | ||||||
| 出版者 | Springer Japan | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0914-7187 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 31605356 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s12149-019-01408-y | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://link.springer.com/article/10.1007%2Fs12149-019-01408-y | |||||
