@article{oai:repo.qst.go.jp:00077706, author = {Fujiwara, Kentaro and B Tsuji, Atsushi and Sudo, Hitomi and Sugyo, Aya and Akiba, Hiroki and Iwanari, Hiroko and Osamu, Kusano-Arai and Tsumoto, Kouhei and Momose, Toshimitsu and Hamakubo, Takao and Higashi, Tatsuya and Kentaro, Fujiwara and Atsushi, Tsuji and Hitomi, Sudo and Aya, Sugyo and Tatsuya, Higashi}, issue = {1}, journal = {Annals of nuclear medicine}, month = {Jan}, note = {Cadherin-17 (CDH17) is a transmembrane protein that mediates cell-cell adhesion and is frequently expressed in adenocarcinomas, including gastric cancer. CDH17 may be an effective diagnostic marker for the staging of gastric cancer. Here, we developed an In-labeled anti-CDH17 monoclonal antibody (Mab) as an imaging tracer and performed biodistribution and single-photon emission computed tomography (SPECT)/computed tomography (CT) imaging studies using mice with CDH17-positive gastric cancer xenografts. CDH17 expression in gastric cancer specimens was also analyzed.}, pages = {13--23}, title = {111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis.}, volume = {34}, year = {2020} }