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Design study of cardiac-dedicated TOF-PET systems with compact detector arrangement
https://repo.qst.go.jp/records/77292
https://repo.qst.go.jp/records/772920f5259a2-fb3b-4175-be1e-758777416322
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-10-02 | |||||
| タイトル | ||||||
| タイトル | Design study of cardiac-dedicated TOF-PET systems with compact detector arrangement | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Akamatsu, Go
× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Takyu, Sodai× Kang, Hangyu× Takahashi, Miwako× Yoshida, Eiji× Yamaya, Taiga× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Takyu, Sodai× Kang, Hangyu× Takahashi, Miwako× Yoshida, Eiji× Yamaya, Taiga |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Coronary artery disease (CAD) is one of the leading causes of death world-wide. Noninvasive quantification of myocardial blood flow with PET is a key tool for detection and monitoring of CAD. However, current standard cylindrical PET scanners are not optimized for cardiac imaging because they are designed mainly for whole-body imaging. In this study, we proposed two compact geometries, the elliptical geometry and the D-shape geometry, for a cardiac-dedicated PET system. We compared their performance with a conventional cylindrical geometry by using the Geant4 simulation toolkit. Furthermore, we evaluated two detector designs with different LYSO crystal thicknesses (20-mm and 10-mm) and appropriate practical coincidence timing resolutions (CTRs) (300 ps for 20 mm LYSO and 250 ps for 10 mm LYSO) to investigate a suitable detector design. In the simulation, an elliptical water phantom (10 MBq) was scanned for 10 s. We evaluated the sensitivity, the noise-equivalent count rate (NECR), and image noise (coefficient of variation: CV) of the water phantom. The D-shape geometry with the 20 mm long LYSO showed the highest sensitivity and NECR. This geometry achieved 71% higher sensitivity and 44% higher NECR compared with the conventional cylindrical geometry. The image noise (CV) was decreased by 24%. The number of detectors was reduced to 3/8 (37.5%). On the other hand, the system with the half-thickness crystal did not show any improvement in the image noise compared with the whole-body cylindrical geometry. With the 20 mm long LYSO, our proposed D-shape geometry is a promising design for a high-sensitivity cardiac-dedicated PET system. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) | |||||
| 発表年月日 | ||||||
| 日付 | 2019-11-01 | |||||
| 日付タイプ | Issued | |||||
