@misc{oai:repo.qst.go.jp:00077292,
 author = {Akamatsu, Go and Tashima, Hideaki and Iwao, Yuma and Takyu, Sodai and Kang, Hangyu and Takahashi, Miwako and Yoshida, Eiji and Yamaya, Taiga and Akamatsu, Go and Tashima, Hideaki and Iwao, Yuma and Takyu, Sodai and Kang, Hangyu and Takahashi, Miwako and Yoshida, Eiji and Yamaya, Taiga},
 month = {Nov},
 note = {Coronary artery disease (CAD) is one of the leading causes of death world-wide. Noninvasive quantification of myocardial blood flow with PET is a key tool for detection and monitoring of CAD. However, current standard cylindrical PET scanners are not optimized for cardiac imaging because they are designed mainly for whole-body imaging. In this study, we proposed two compact geometries, the elliptical geometry and the D-shape geometry, for a cardiac-dedicated PET system. We compared their performance with a conventional cylindrical geometry by using the Geant4 simulation toolkit. Furthermore, we evaluated two detector designs with different LYSO crystal thicknesses (20-mm and 10-mm) and appropriate practical coincidence timing resolutions (CTRs) (300 ps for 20 mm LYSO and 250 ps for 10 mm LYSO) to investigate a suitable detector design. In the simulation, an elliptical water phantom (10 MBq) was scanned for 10 s. We evaluated the sensitivity, the noise-equivalent count rate (NECR), and image noise (coefficient of variation: CV) of the water phantom. The D-shape geometry with the 20 mm long LYSO showed the highest sensitivity and NECR. This geometry achieved 71% higher sensitivity and 44% higher NECR compared with the conventional cylindrical geometry. The image noise (CV) was decreased by 24%. The number of detectors was reduced to 3/8 (37.5%). On the other hand, the system with the half-thickness crystal did not show any improvement in the image noise compared with the whole-body cylindrical geometry. With the 20 mm long LYSO, our proposed D-shape geometry is a promising design for a high-sensitivity cardiac-dedicated PET system., 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)},
 title = {Design study of cardiac-dedicated TOF-PET systems with compact detector arrangement},
 year = {2019}
}