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Assessment of SPECT-CT fusion images and semi-quantitative evaluation of I-123 IMP SPECT in patients with ocular choroidal melanoma.
https://repo.qst.go.jp/records/75679
https://repo.qst.go.jp/records/7567900ff2d40-7719-49fe-93f4-4fafbbd84d43
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-04-23 | |||||
| タイトル | ||||||
| タイトル | Assessment of SPECT-CT fusion images and semi-quantitative evaluation of I-123 IMP SPECT in patients with ocular choroidal melanoma. | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
山崎, 香奈
× 山崎, 香奈× 西井, 龍一× 東, 達也× 牧島, 弘和× 粕谷, 吾朗× 辻, 比呂志× 吉永, 恵一郎× 鎌田, 正× Yamazaki, Kana× Nishii, Ryuichi× Higashi, Tatsuya× Makishima, Hirokazu× Kasuya, Goro× Tsuji, Hiroshi× Yoshinaga, Keiichiro× Kamada, Tadashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Objective] Choroidal melanoma is the most common primary ocular malignant tumor. I-123 IMP SPECT imaging was reported to be useful diagnostic imaging tool, however the diagnostic values in terms of assessment of fused image with CT/MRI and the semi-quantitative evaluation of the IMP-SPECT are still left to be discussed. [Materials and Methods] Among patients who visited our institution for carbon-ion radiotherapy, ten patients who received I-123 IMP SPECT imaging were enrolled in this investigation. Fifteen min and 24 hours after intravenous injection of the radiotracer, SPECT imaging was performed using a gamma camera (E.CAM, Canon Medical, Tokyo, Japan). All acquired SPECT images were fused with CT or MRI images using a fusion viewer software (AZE-Hayabusa, AZE, Japan). ROIs of the tumor, contralateral normal choroidal tissue and normal soft tissue referring to CT or MRI image were analyzed, followed by semi-quantitative evaluation was assessed using non-parametric Wilcoxon rank sum test. [Results] All tumors were visualized clearly in the 24h-SPECT image than those in 15min-SPECT image. The uptake index (UI) of the tumor: (tumor count) / (normal soft tissue count) and the contralateral normal choroidal tissue: (normal choroidal tissue count) / (normal soft tissue count) were 3.16+/-0.97 and 1.35+/-0.17, respectively (p < 0.001). The tumor-to-normal tissue ratios was 7.78+/-5.10. [Conclusion] I-123 IMP SPECT imaging performed 24h after injection of the radiotracer and fusion-image-analysis with CT or MRI were useful for detection of the choroidal melanoma. Also semi-quantitative evaluation using the fused images using tumor-UI and T/N ratio were considered to be valuable imaging techniques for diagnosis of the choroidal melanoma. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第78回日本医学放射線学会総会 | |||||
| 発表年月日 | ||||||
| 日付 | 2019-04-14 | |||||
| 日付タイプ | Issued | |||||
