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Analysis of Response Deficient Mutants of Streptomyces coelicolor to Contact-dependent Stimuli
https://repo.qst.go.jp/records/74722
https://repo.qst.go.jp/records/747225f0b94b1-3daf-427c-85d0-a90ee7882bda
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2019-03-13 | |||||
タイトル | ||||||
タイトル | Analysis of Response Deficient Mutants of Streptomyces coelicolor to Contact-dependent Stimuli | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Asamizu, Syumpei
× Asamizu, Syumpei× Yanagisawa, Masaomi× Ishizuka, Takumi× 佐藤, 勝也× 大野, 豊× Onaka, Hiroyasu× Sato, Katsuya× Ono, Yutaka |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Actinomycetes, gram-positive bacteria, have been known as a majour source of bioactive natural product which can be drug candidates. Object of this study is to elucidate the gene(s) which are involved in the response for activation of secondary metabolism within actinomycetes. Elucidation of the mechanism can be expected to lead for creation of genetic tools to generate novel bioactive natural products. In this study, we examined a mutant library of Streptomyces coelicolor generated by carbon ion beams irradiation. As a result, mutants obtained from 100 Gy irradiation contained average 2.0 mutations (14 mutations in 7 mutants). Mutants obtained from 200 Gy irradiation contained average 3.3 mutations (30 mutations in 9 mutants). | |||||
書誌情報 |
QST Takasaki Annual Report 2017 p. 106, 発行日 2019-03 |