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Comparison of diffusion-weighted MRI and anti-Stokes Raman scattering (CARS) measurements of the inter-compartmental exchange-time of water in expression-controlled aquaporin-4 cells.
https://repo.qst.go.jp/records/73837
https://repo.qst.go.jp/records/7383710baeb09-707f-4537-bcd8-a5bfa8b1e884
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-02-25 | |||||
| タイトル | ||||||
| タイトル | Comparison of diffusion-weighted MRI and anti-Stokes Raman scattering (CARS) measurements of the inter-compartmental exchange-time of water in expression-controlled aquaporin-4 cells. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Obata, Takayuki
× Obata, Takayuki× Kershaw, Jeff× Tachibana, Yasuhiko× Miyauchi, Takayuki× Abe, Yoichiro× Shibata, Sayaka× Kawaguchi, Hiroshi× Ikoma, Yoko× Takuwa, Hiroyuki× Aoki, Ichio× Yasui, Masato× Obata, Takayuki× Kershaw, Jeffrey× Tachibana, Yasuhiko× Shibata, Sayaka× Kawaguchi, Hiroshi× Ikoma, Yoko× Takuwa, Hiroyuki× Aoki, Ichio |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We performed multi-b and multi-diffusion-time diffusion-weighted magnetic resonance imaging on aquaporin-4-expressing (AQ) and -non-expressing (noAQ) cells, and demonstrated a clear difference between the signals from the two cell types. The data were interpreted using a two-compartment (intra and extracellular spaces) model including inter-compartmental exchange. It was also assumed that restricted diffusion of water molecules inside the cells leads to the intracellular diffusion coefficient being inversely proportional to the diffusion-time. Estimates of the water-exchange-times obtained with this model are compared to those measured using an independent optical imaging technique (coherent anti-Stokes Raman scattering imaging, CARS). For both techniques it was found that the exchange-time estimated for the noAQ cells was significantly longer than that for the AQ cells. | |||||
| 書誌情報 |
Scientific reports 巻 8, 号 1, p. 17954, 発行日 2018-12 |
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| 出版者 | ||||||
| 出版者 | Nature Publishing Group | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2045-2322 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 30560905 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1038/s41598-018-36264-9 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.nature.com/articles/s41598-018-36264-9 | |||||
