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Studies on radiation induced defensive cellular communication using SPICE-NIRS microbeam (S16-IOL01: 2018)
https://repo.qst.go.jp/records/73430
https://repo.qst.go.jp/records/73430b84335d3-ca4a-40eb-b05a-2df9984fe949
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2019-02-18 | |||||
タイトル | ||||||
タイトル | Studies on radiation induced defensive cellular communication using SPICE-NIRS microbeam (S16-IOL01: 2018) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Teruaki, Konishi
× Teruaki, Konishi× Jun Wang× Tengku Ahbrizal Tengku Ahmad× Narongchai Autsavapromporn× Masakazu Oikawa× Alisa Kobayashi× Yoshiya Furusawa |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In classical radiation biology, it is described that initial DNA damages induced directly by energy deposition of radiation are the main cause for the varieties of radiobiological consequences, thus the DNA is considered to be the primary target of radiation. However, in the past few decades, there are many phenomena were reported that cannot be explained by this classical dogma. These findings indicated the existence of non-DNA/secondary targets, that may affect the fate of irradiated and nearby non-irradiated cells. The possibility is that this non-DNA/secondary target has been activated by direct energy deposition in the cytoplasm. Our aim is to provide answers to questions such as what is the non-DNA/secondary target and how does it involve with the damages in the primary target. Therefore microbeam technology would be the effective method to fulfill our demands. | |||||
書誌情報 |
平成28年度共用施設(PASTA&SPICE, NASBEE, X/γ線照射装置)成果報告書 p. 29-31, 発行日 2018-12 |
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出版者 | ||||||
出版者 | 国立研究開発法人量子科学技術研究開発機構 |