@article{oai:repo.qst.go.jp:00073430, author = {Teruaki, Konishi and Jun Wang and Tengku Ahbrizal Tengku Ahmad and Narongchai Autsavapromporn and Masakazu Oikawa and Alisa Kobayashi and Yoshiya Furusawa}, journal = {平成28年度共用施設(PASTA&SPICE, NASBEE, X/γ線照射装置)成果報告書}, month = {Dec}, note = {In classical radiation biology, it is described that initial DNA damages induced directly by energy deposition of radiation are the main cause for the varieties of radiobiological consequences, thus the DNA is considered to be the primary target of radiation. However, in the past few decades, there are many phenomena were reported that cannot be explained by this classical dogma. These findings indicated the existence of non-DNA/secondary targets, that may affect the fate of irradiated and nearby non-irradiated cells. The possibility is that this non-DNA/secondary target has been activated by direct energy deposition in the cytoplasm. Our aim is to provide answers to questions such as what is the non-DNA/secondary target and how does it involve with the damages in the primary target. Therefore microbeam technology would be the effective method to fulfill our demands.}, pages = {29--31}, title = {Studies on radiation induced defensive cellular communication using SPICE-NIRS microbeam (S16-IOL01: 2018)}, year = {2018} }