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Analysis of the picosecond dynamics of muscle contractile proteins and their hydration water by quasielastic neutron scattering
https://repo.qst.go.jp/records/73335
https://repo.qst.go.jp/records/733355481aa2f-585d-4780-8270-6e95758740ff
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-10-16 | |||||
| タイトル | ||||||
| タイトル | Analysis of the picosecond dynamics of muscle contractile proteins and their hydration water by quasielastic neutron scattering | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
松尾, 龍人
× 松尾, 龍人× 荒田敏昭× 小田俊郎× 中島健次× 河村聖子× 菊地龍弥× 富永大輝× 柴田薫× 河野, 史明× 藤原, 悟× 松尾 龍人× 河野 史明× 藤原 悟 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Quasielastic neutron scattering (QENS) is a powerful tool to study the picosecond dynamics of proteins and their hydration water. Picosecond motions of proteins are known to facilitate structural changes required for biological functions, and are affected by the dynamics of their hydration water. Characterization of these motions is thus crucial for elucidating the mechanism of protein functions. In this talk, we will describe our recent QENS studies on muscle contractile proteins and their hydration water. We found that each protein shows distinct protein dynamics and hydration water mobility, and that a disease-causing mutation modulates protein dynamics. Based on these findings, how the picosecond dynamics is correlated with muscle contraction will be discussed. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第56回日本生物物理学会年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-09-15 | |||||
| 日付タイプ | Issued | |||||
