@misc{oai:repo.qst.go.jp:00073335, author = {松尾, 龍人 and 荒田敏昭 and 小田俊郎 and 中島健次 and 河村聖子 and 菊地龍弥 and 富永大輝 and 柴田薫 and 河野, 史明 and 藤原, 悟 and 松尾 龍人 and 河野 史明 and 藤原 悟}, month = {Sep}, note = {Quasielastic neutron scattering (QENS) is a powerful tool to study the picosecond dynamics of proteins and their hydration water. Picosecond motions of proteins are known to facilitate structural changes required for biological functions, and are affected by the dynamics of their hydration water. Characterization of these motions is thus crucial for elucidating the mechanism of protein functions. In this talk, we will describe our recent QENS studies on muscle contractile proteins and their hydration water. We found that each protein shows distinct protein dynamics and hydration water mobility, and that a disease-causing mutation modulates protein dynamics. Based on these findings, how the picosecond dynamics is correlated with muscle contraction will be discussed., 第56回日本生物物理学会年会}, title = {Analysis of the picosecond dynamics of muscle contractile proteins and their hydration water by quasielastic neutron scattering}, year = {2018} }