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Helmet PET enabling high sensitivity brain imaging toward early diagnosis of dementia
https://repo.qst.go.jp/records/72606
https://repo.qst.go.jp/records/72606f52f4efa-e68f-42d0-87d0-a9ef28d6db9b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-12-25 | |||||
| タイトル | ||||||
| タイトル | Helmet PET enabling high sensitivity brain imaging toward early diagnosis of dementia | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
田島, 英朗
× 田島, 英朗× 吉田, 英治× 岩男, 悠真× 脇坂, 秀克× 前田, 貴雅× 高堂, 裕平× 関, 千江× 樋口, 真人× 須原, 哲也× 山下, 大地× 山谷, 泰賀× Tashima, Hideaki× Yoshida, Eiji× Iwao, Yuma× Wakizaka, Hidekatsu× Maeda, Takamasa× Takado, Yuhei× Seki, Chie× Higuchi, Makoto× Suhara, Tetsuya× Yamashita, Taichi× Yamaya, Taiga |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We are developing high sensitivity dedicated brain PET, helmet PET, which has a spherically arranged detector unit and add-on detector unit for improving sensitivity at low cost. There are emerging demands for such dedicated brain PET imaging for early diagnosis of dementia, because several diagnostic tracers for Alzheimer’s disease have been developed. The hemispherical arrangement of the detector can improve the sensitivity for the brain region significantly. In addition, the add-on detector can significantly improve the sensitivity at the center, where the sensitivity without the add-on detector is still low as the same as the conventional cylindrical PET. For a proof-of-concept, we first developed the helmet-chin PET having the add-on detectors at chin position. Next, we developed the helmet-neck PET prototype because, in theory, the effect of the add-on detector is equivalent no matter its position. We evaluated basic performance of the prototypes and conducted healthy volunteer study with 18F-FDG. Sensitivity composition showed the helmet-neck PET had higher sensitivity for brain region because the neck detector can be placed closer than the chin detector which required safety margin in designing. The result showed that the helmet PET with add-on detector had promising performance for high-sensitivity and high-resolution brain imaging with reduced cost. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 1st QST International Symposium Quantum Life Science | |||||
| 発表年月日 | ||||||
| 日付 | 2017-07-25 | |||||
| 日付タイプ | Issued | |||||
