@misc{oai:repo.qst.go.jp:00072606,
 author = {田島, 英朗 and 吉田, 英治 and 岩男, 悠真 and 脇坂, 秀克 and 前田, 貴雅 and 高堂, 裕平 and 関, 千江 and 樋口, 真人 and 須原, 哲也 and 山下, 大地 and 山谷, 泰賀 and Tashima, Hideaki and Yoshida, Eiji and Iwao, Yuma and Wakizaka, Hidekatsu and Maeda, Takamasa and Takado, Yuhei and Seki, Chie and Higuchi, Makoto and Suhara, Tetsuya and Yamashita, Taichi and Yamaya, Taiga},
 month = {Jul},
 note = {We are developing high sensitivity dedicated brain PET, helmet PET, which has a spherically arranged detector unit and add-on detector unit for improving sensitivity at low cost. There are emerging demands for such dedicated brain PET imaging for early diagnosis of dementia, because several diagnostic tracers for Alzheimer’s disease have been developed. The hemispherical arrangement of the detector can improve the sensitivity for the brain region significantly. In addition, the add-on detector can significantly improve the sensitivity at the center, where the sensitivity without the add-on detector is still low as the same as the conventional cylindrical PET. For a proof-of-concept, we first developed the helmet-chin PET having the add-on detectors at chin position. Next, we developed the helmet-neck PET prototype because, in theory, the effect of the add-on detector is equivalent no matter its position. We evaluated basic performance of the prototypes and conducted healthy volunteer study with 18F-FDG. Sensitivity composition showed the helmet-neck PET had higher sensitivity for brain region because the neck detector can be placed closer than the chin detector which required safety margin in designing. The result showed that the helmet PET with add-on detector had promising performance for high-sensitivity and high-resolution brain imaging with reduced cost., 1st QST International Symposium Quantum Life Science},
 title = {Helmet PET enabling high sensitivity brain imaging toward early diagnosis of dementia},
 year = {2017}
}