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Model building of overlapping dinucleosome from SAXS and SANS data
https://repo.qst.go.jp/records/72439
https://repo.qst.go.jp/records/7243931790644-de5c-457a-95c8-b47f826b4550
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-09-13 | |||||
| タイトル | ||||||
| タイトル | Model building of overlapping dinucleosome from SAXS and SANS data | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Atsushi
× Matsumoto, Atsushi× Kono, Hidetoshi× Inoue, Rintaro× Sugiyama, Masaaki× Kato, Daiki× Arimura, Yasuhiro× Kurumizaka, Hitoshi× 松本 淳× 河野 秀俊 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In this study, we built the atomic models of the overlapping dinucleosome in solution by the computational approach based on the experimental data of the small-angle X-ray scattering (SAXS) and the small-angle neutron scattering (SANS). In this computational approach, first, the initial atomic model is deformed by the simulation techniques to generate a lot of deformed atomic models with different conformations. Then, the SAXS and SANS profiles are computed from each deformed atomic model. Finally, these computed profiles are compared with the experimental ones to find the best-fitting atomic models. For the accurate reproduction of the experimental data, it was important to model correctly the histone tails, which are not observed in the X-ray crystal structure. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日本生物物理学会第55回年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2017-09-20 | |||||
| 日付タイプ | Issued | |||||
