{"_buckets": {"deposit": "51513482-e93e-429f-8810-678f2a8f3f2f"}, "_deposit": {"created_by": 1, "id": "71850", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "71850"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00071850", "sets": ["28"]}, "author_link": ["707465", "707456", "707457", "707455", "707469", "707462", "707463", "707467", "707460", "707468", "707453", "707464", "707461", "707466", "707459", "707454", "707458"], "item_10005_date_7": {"attribute_name": "発表年月日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2015-11-06", "subitem_date_issued_type": "Issued"}]}, "item_10005_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "我々は、患者がん細胞を培養する新技術Cancer Tissue Originated Spheroid(CTOS)を用いた検討に基づき、HER3をがんの難治性に係る因子の一つと考え、HER3のPETイメージングの可能性について、Zr-89 標識抗HER3抗体(Mab#58)を用いて検討してきた。これまでに報告したHER3過剰発現がん細胞株移植腫瘍および大腸癌由来のCTOS C45の陽性描出に加え、今回は、肺がん由来のCTOS OMLC-5移植腫瘍のPET撮像を行い、これまでの結果とあわせ、Zr-89標識 Mab#58により、患者がんの性質を反映し、かつ、HER3の増殖への関与が確認されているCTOSの移植腫瘍モデルにおいて、HER3の特異的なPETイメージングが可能なことを示した。以上より、Zr-89標識抗HER3抗体によるPETイメージングは、HER3標的するin vivoイメージング法として有望と考えられた。", "subitem_description_type": "Abstract"}]}, "item_10005_description_6": {"attribute_name": "会議概要（会議名, 開催地, 会期, 主催者等）", "attribute_value_mlt": [{"subitem_description": "第55回日本核医学会学術総会", "subitem_description_type": "Other"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "元, 清華"}], "nameIdentifiers": [{"nameIdentifier": "707453", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "古川, 高子"}], "nameIdentifiers": [{"nameIdentifier": "707454", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "辻, 厚至"}], "nameIdentifiers": [{"nameIdentifier": "707455", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "永津, 弘太郎"}], "nameIdentifiers": [{"nameIdentifier": "707456", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "遠藤, 洋子"}], "nameIdentifiers": [{"nameIdentifier": "707457", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "井上, 正宏"}], "nameIdentifiers": [{"nameIdentifier": "707458", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "益子, 高"}], "nameIdentifiers": [{"nameIdentifier": "707459", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "張, 明栄"}], "nameIdentifiers": [{"nameIdentifier": "707460", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐賀, 恒夫"}], "nameIdentifiers": [{"nameIdentifier": "707461", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "藤林, 康久"}], "nameIdentifiers": [{"nameIdentifier": "707462", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "元 清華", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707463", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "古川 高子", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707464", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "辻 厚至", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707465", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "永津 弘太郎", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707466", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "張 明栄", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707467", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐賀 恒夫", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707468", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "藤林 康久", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "707469", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "conference object", "resourceuri": "http://purl.org/coar/resource_type/c_c94f"}]}, "item_title": "HER3を標的とするZr-89 標識抗体によるPETイメージング：CTOS移植腫瘍での検討 ", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "HER3を標的とするZr-89 標識抗体によるPETイメージング：CTOS移植腫瘍での検討 "}]}, "item_type_id": "10005", "owner": "1", "path": ["28"], "permalink_uri": "https://repo.qst.go.jp/records/71850", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-11-11"}, "publish_date": "2015-11-11", "publish_status": "0", "recid": "71850", "relation": {}, "relation_version_is_last": true, "title": ["HER3を標的とするZr-89 標識抗体によるPETイメージング：CTOS移植腫瘍での検討 "], "weko_shared_id": -1}