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Assessment of lung parenchyma and metastasis tumor using ultra-short echo-time (UTE) MRI with contrast agents
https://repo.qst.go.jp/records/70863
https://repo.qst.go.jp/records/708639db8fbb4-36e4-4e9e-8c31-a3c0c9d4125a
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-09-04 | |||||
| タイトル | ||||||
| タイトル | Assessment of lung parenchyma and metastasis tumor using ultra-short echo-time (UTE) MRI with contrast agents | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kokuryo, Daisuke
× Kokuryo, Daisuke× Aoki, Ichio× Saga, Tsuneo× 國領 大介× 青木 伊知男× 佐賀 恒夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction: We have developed multi-functional liposomal nanoprobes containing a MR contrast agent, a fluorescence dye and an anticancer drug. In a previous study, subcutaneous and deep-seated tumor could be detected and visualized with the nanoprobes (Kokuryo D, et al: Proc. ISMRM 2010; etc). As the next step, we wish to apply the nanoprobes to lung tumors and other pulmonary disease. However, it is difficult to detect signal in the lung using conventional MR imaging techniques because of low proton density, short T2 *, strong susceptibility effects and respiratory motion. Recently, ultra-short echo-time (UTE) imaging has been developed (Gewalt SL, et al: Magn Reson Med., 1993; etc) and utilized to evaluate the signal changes in lung parenchyma for various animal models (Takahashi M: J Magn Reson Imaging, 2010; etc). As a preliminary step toward theragnostics using nanoprobe-based contrast agents such as Gd-DTPA/DACHPt-loaded micelles (Kaida S: Cancer Res., 2010), in this study Gd-chelate contrast agents were evaluated for MRI of lung parenchyma and metastatic tumor. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2011 Worsl Molecular Imaging Congress (Wmic) | |||||
| 発表年月日 | ||||||
| 日付 | 2011-09-10 | |||||
| 日付タイプ | Issued | |||||
