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Carbon ion radiotherapy for localized primary sarcoma of the extremities
https://repo.qst.go.jp/records/69934
https://repo.qst.go.jp/records/699343af5a4f2-ab9e-4179-bea1-76fff88bd847
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-11-10 | |||||
| タイトル | ||||||
| タイトル | Carbon ion radiotherapy for localized primary sarcoma of the extremities | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Sugahara, Shinji
× Sugahara, Shinji× Kamada, Tadashi× Imai, Reiko× Tsuji, Hiroshi× Suzuki, Motohisa× Okada, Tohru× Tsujii, Hirohiko× Tatezaki, Shinichiroh× 菅原 信二× 鎌田 正× 今井 礼子× 辻 比呂志× 鈴木 志恒× 岡田 徹× 辻井 博彦× 舘崎 愼一郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | OBJECTIVE: To determine the effectiveness of carbon ion radiotherapy (CIRT) for localized primary sarcoma of the extremities. PATIENTS AND METHODS: From April 2000 to February 2009, 16 (male/female:11/5) patients with localized primary sarcoma of the extremities received CIRT. Age ranged from 14 to 83 years (median 53 years). Nine patients had primary diseases and 7 had recurrent diseases. Of 16 patients, 8 refused amputation, remaining 8 refused surgical resection. Tumors located upper limbs in 4 patients and lower limbs in 12. Histological diagnoses were as follows: malignant fibrous histiocytoma in 4, osteoarcoma in 3, malignant peripheral nerve sheath tumor in 2, synovial sarcoma in 2, and miscellaneous in 5 patients. The CIRT dose to the limb was 52.8 GyE for 1 patient, 64GyE for 4, 70.4GyE for 11 in fixed16 fractions over 4weeks. Records were reviewed and outcomes including radiologic response, local control (progression-free), and survival were analyzed. RESULTS: The median follow-up was 25 months (range: 5 to 70 months). Radiological response rate was 56% (PR in 9, SD in 6, PD in 1). The local control rates at 4 years were 75%. The overall survival rates at 4 years were 69%. 12 Of 16 patients were alive without disease progression, 3 patients were died due to systemic disease and remaining one was died due to leukemia 57 months after CIRT. No toxicity greater than Grade 2 was observed. CONCLUSION: CIRT is suggested to be an effective and safe treatment for patients who refused surgery with localized primary sarcoma of the extremities. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 15th Annual CTOS Meeting | |||||
| 発表年月日 | ||||||
| 日付 | 2009-11-07 | |||||
| 日付タイプ | Issued | |||||
