WEKO3
アイテム
DEBE-DB (Differential-Equation-Based Edge database): a database of ab initio predicted gene interactions for cell line THP1
https://repo.qst.go.jp/records/69681
https://repo.qst.go.jp/records/69681107f9d7b-e6d8-477c-a587-b4cd24057642
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-02-09 | |||||
| タイトル | ||||||
| タイトル | DEBE-DB (Differential-Equation-Based Edge database): a database of ab initio predicted gene interactions for cell line THP1 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
坂田, 克己
× 坂田, 克己× 石井, 秀始× 佐藤, 伸司× 河合, 淳× 齋藤, 俊行× その他× 坂田 克己× 石井 秀始× 齋藤 俊行 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The DEBE-DB was developed to provide ab initio predicted gene interactions. These interactions were predicted by fitting large scale temporal expression profiles to the S-system, a non-linear differential equation model, using an original high speed algorithm. A z-score is calculated for each interaction based on its goodness-of-fit. The database contains nearly 13,000 candidate gene interactions which were predicted based on temporal expression profiles of PMA (Phorbol Myristate Acetate)-treated THP-1 (Human acute monocytic leukemia cell line) of two biological replicas. The expression profiles used for the prediction were high-quality data of qRT-PCR (quantitative Real-Time Reverse Transcription Polymerase Chain Reaction) provided by the Genome Network Project. The web interface allows the user to identify statistically significant gene interactions with z-scores greater than a cut-off value. DEBE-DB is freely available at http://debe-db.nirs.go.jp/ | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第5回 ゲノムネットワークプロジェクト公開シンポジウム | |||||
| 発表年月日 | ||||||
| 日付 | 2009-01-16 | |||||
| 日付タイプ | Issued | |||||
