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Free radical reactions in an aqueous sample caused by heavy-ion (carbon) beam irradiation
https://repo.qst.go.jp/records/69606
https://repo.qst.go.jp/records/69606f31b6722-1d5a-43c4-bc90-d4948c6977d5
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-11-28 | |||||
| タイトル | ||||||
| タイトル | Free radical reactions in an aqueous sample caused by heavy-ion (carbon) beam irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Kenichiro
× Matsumoto, Kenichiro× Nakanishi, Ikuo× Endo, Kazutoyo× Anzai, Kazunori× 松本 謙一郎× 中西 郁夫× 安西 和紀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | High LET carbon ion beam cancer therapy using the Heavy-Ion Medical Accelerator in Chiba (HIMAC) (National Institute of Radiological Sciences, Chiba, Japan) began in 1994. The total number of patients who have undergone cancer therapy at HIMAC is now 4007 (at June 4, 2008). Considering the popularity of the heavy-ion cancer therapy in the future, its quality and accuracy must be improved and optimized. The oxygen effect is supposed to decrease by using high LET irradiation such as heavy-ion beams, but cannot be eliminated completely. Hydroxyl radical generation by heavy-ion beam irradiation to an aqueous sample was reported. Increasing cell viability made by DMSO in a heavy-ion irradiated cultured cell sample was reported. Those facts suggest that the effect of heavy-ion beams can be modified by regulating redox reactions. Detection of oxygen free radical reactions and mapping its geometry is still important to regulate the oxygen effect of high LET irradiation. In this presentation, the detection of free radical reactions in a gelatin sample irradiated by a heavy-ion beam was tested using EPR spectroscopic and MRI methods. The geometry of free radical generation and its LET dependence in the sample is discussed. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | SFRBM's 15th Annual Meeting | |||||
| 発表年月日 | ||||||
| 日付 | 2008-11-23 | |||||
| 日付タイプ | Issued | |||||
