@misc{oai:repo.qst.go.jp:00069606,
 author = {Matsumoto, Kenichiro and Nakanishi, Ikuo and Endo, Kazutoyo and Anzai, Kazunori and 松本 謙一郎 and 中西 郁夫 and 安西 和紀},
 month = {Nov},
 note = {High LET carbon ion beam cancer therapy using the Heavy-Ion Medical Accelerator in Chiba (HIMAC) (National Institute of Radiological Sciences, Chiba, Japan) began in 1994. The total number of patients who have undergone cancer therapy at HIMAC is now 4007 (at June 4, 2008). Considering the popularity of the heavy-ion cancer therapy in the future, its quality and accuracy must be improved and optimized.
The oxygen effect is supposed to decrease by using high LET irradiation such as heavy-ion beams, but cannot be eliminated completely. Hydroxyl radical generation by heavy-ion beam irradiation to an aqueous sample was reported. Increasing cell viability made by DMSO in a heavy-ion irradiated cultured cell sample was reported. Those facts suggest that the effect of heavy-ion beams can be modified by regulating redox reactions. Detection of oxygen free radical reactions and mapping its geometry is still important to regulate the oxygen effect of high LET irradiation. In this presentation, the detection of free radical reactions in a gelatin sample irradiated by a heavy-ion beam was tested using EPR spectroscopic and MRI methods. The geometry of free radical generation and its LET dependence in the sample is discussed., SFRBM's 15th Annual Meeting},
 title = {Free radical reactions in an aqueous sample caused by heavy-ion (carbon) beam irradiation},
 year = {2008}
}