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Expression of brain-type fatty acid-binding protein (Fabp7) in medaka development.
https://repo.qst.go.jp/records/69248
https://repo.qst.go.jp/records/6924864d7c239-7b52-49d3-ae7c-05cfc75e85f8
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-12-26 | |||||
| タイトル | ||||||
| タイトル | Expression of brain-type fatty acid-binding protein (Fabp7) in medaka development. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Fujimori, Akira
× Fujimori, Akira× Maruyama, Kouichi× Yasuda, Takako× Kubota, Yoshihisa× Takahashi, Sentaro× Ishikawa, Yuuji× 藤森 亮× 丸山 耕一× 久保田 善久× 高橋 千太郎× 石川 裕二 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Fatty acid binding proteins (fabp) are a multigene family of small intracellular proteins that bind hydrophobic ligands. Recent studies have indicated that brain-type fabp plays important roles in neurogenesis or neuronal migration in vertebrates. We isolated the cDNA and the genomic fragment containing the fabp7 gene for medaka fish and examined the expression of the gene through the development of their central nervous system (CNS). The medaka fabp7 gene consists of four exons in approximately 1 kb of the genomic region. Its deduced amino acid sequence exhibits over 80% identity with those of the other higher vertebra. In situ hybridization analyses demonstrated that fabp7 positive cells first appear at st.22 in a small dorsal domain of the retina, dorsal diencephalon and rhombencephalon, then expand to the whole CNS including the retina and spinal cord. In addition, we generated two lines of transgenic medaka with 1.7 kb upstream of the fabp7 gene combined with an enhanced-green fluorescence protein gene (EGFP) as the reporter. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第30会日本分子生物学会年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2007-12-15 | |||||
| 日付タイプ | Issued | |||||
