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Enhanced Radical-Scavenging Activity of Artepillin C Derivatives
https://repo.qst.go.jp/records/68933
https://repo.qst.go.jp/records/68933246d9f66-bffa-4fd4-8117-dd137aaaee02
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-05-07 | |||||
| タイトル | ||||||
| タイトル | Enhanced Radical-Scavenging Activity of Artepillin C Derivatives | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nakanishi, Ikuo
× Nakanishi, Ikuo× Ohkubo, Kei× Uto, Yoshihiro× Kawashima, Tomonori× Manda, Sushma× Kanazawa, Hideko× Hori, Hitoshi× Fukuhara, Kiyoshi× Okuda, Haruhiro× Ozawa, Toshihiko× Ikota, Nobuo× Fukuzumi, Shunichi× Anzai, Kazunori× 中西 郁夫× Ｍａｎｄａ Ｓｕｓｈｍａ× 小澤 俊彦× 安西 和紀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Artepillin C, a major component of Brazilian propolis, is known to act as an antioxidant, which efficiently scavenges reactive oxygen species generated in the biological systems. In order to improve the radical-scavenging activity of artepillin C, we synthesized four artepillin C derivatives and compared their scavenging rate constants of cumylperoxyl radical in propionitrile at 203 K by the electron spin resonance (ESR) technique. More than two-fold higher scavenging activity of cumylperoxyl radical as compared to Artepillin C was observed with a derivative, where the isoprenyl and carboxyl groups in Artepillin C are substituted by methoxy and hydroxymethyl groups, respectively. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Experimental Biology Annual Meeting 2007 (EB2007) | |||||
| 発表年月日 | ||||||
| 日付 | 2007-05-02 | |||||
| 日付タイプ | Issued | |||||
